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Clinical characteristics and serological profiles of Lyme disease in children: a 15-year retrospective cohort study in Switzerland.
Lancet Reg Health Eur
January 2025
Division of Infectious Diseases and Hospital Epidemiology, Children's Research Center, University Children's Hospital Zurich, University of Zurich, Zurich, Switzerland.
Background: Lyme disease (LD) is caused by and is the most common tickborne disease in the northern hemisphere. Although classical characteristics of LD are well-known, the diagnosis and treatment are often delayed. Laboratory diagnosis by serological testing is recommended for most LD manifestations.
View Article and Find Full Text PDFCase report of disseminated borrelial lymphocytoma with isolation of sensu stricto in chronic lymphatic leukemia stage Binet A-an 11 year follow up.
Front Med (Lausanne)
October 2024
National Reference Center for Borrelia, Bavarian Health and Food Safety Authority, Oberschleissheim, Germany.
Article Synopsis
- The case report describes a patient with chronic lymphocytic B cell leukemia (B-CLL) who developed skin lesions that were initially misdiagnosed as leukemia cutis but were later identified as cutaneous borreliosis (specifically lymphocytoma).
- Borrelia bacteria were successfully isolated from the patient’s skin lesions, and antibiotic treatment resulted in significant improvement, although a second course of antibiotics was necessary for full resolution.
- After 11 years of follow-up, the patient remained free of skin lesions and stable in her B-CLL condition without needing chemotherapy, highlighting the interplay between Lyme disease and pre-existing malignancies.
Skin Changes in Suspected Lyme Disease.
Acta Dermatovenerol Croat
December 2023
Pero Vržogić, MD, Naftalan Special Hospital for Medical Rehabilitation, Ivanić Grad, Croatia;
Article Synopsis
- Ticks are a significant health concern in Croatia and worldwide due to their role in transmitting various diseases, including Lyme borreliosis, which is caused by the Borrelia burgdorferi bacterium.
- In Croatia, the incidence rate of Lyme borreliosis is approximately 6.51 cases per 100,000 people, highlighting the risk of infection from ticks.
- The article describes a case of a 58-year-old woman with Lyme disease who had skin manifestations that fully regressed after successful treatment, demonstrating the importance of early diagnosis and intervention.
Pediatric Lyme Disease in Northern Italy: An 18-Year Single-Center Case Series.
Microorganisms
February 2024
Pediatric Infectious Disease Unit, Università degli Studi di Milano, L. Sacco Hospital, Via G.B. Grassi 74, 20157 Milan, Italy.
Article Synopsis
- The study investigates pediatric Lyme borreliosis (LB) in Europe, specifically an 18-year case series involving 130 children suspected of having LB, revealing significant regional differences in incidence and challenges in diagnosis.
- Out of the patients, 34% were confirmed with LB, with a median age of six years; a notable percentage, over 70%, had a history of tick bites, primarily from the Po River valley region.
- The findings indicate a need for improved awareness and adherence to Lyme disease management protocols among healthcare providers, as many children presented with non-specific symptoms and there was a notable issue with over-prescription of antibiotics.
Article Synopsis
- Borrelial pseudolymphoma, also known as Borrelia lymphocytoma, is a rare skin condition related to Lyme disease, primarily affecting children after being infected with Borrelia afzelii, which is spread by Ixodes ricinus ticks.
- The most common areas for this condition to manifest are the earlobe, scrotum, nipples, and areomamillary complex, making its occurrence in a 58-year-old female patient unexpected.
- The article emphasizes the rising prevalence of Lyme disease and its unusual symptoms, highlighting that most cases can be treated without the need for surgery.
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