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Impact of Post Percutaneous Coronary Intervention Fractional Flow Reserve on 5-Year Clinical Outcomes (The FFR SEARCH Study).
Catheter Cardiovasc Interv
March 2025
Department of (Interventional) Cardiology, Thoraxcenter, Erasmus University Medical Center, Rotterdam, the Netherlands.
Background: Fractional flow reserve (FFR) following percutaneous coronary intervention (PCI) can be used to evaluate procedural success and to guide stent optimization. Several studies have demonstrated that lower FFR after stent implantation is associated with increased adverse event rates up to 2 years. However, the impact of post-PCI FFR on very long-term clinical outcome remains unknown.
View Article and Find Full Text PDFThe Impact of SNP Score on Low-Density Lipoprotein Cholesterol Concentration and Coronary Artery Disease.
Int J Mol Sci
March 2025
Institute of Cardiology, Lithuanian University of Health Sciences, Sukileliu 15, 50103 Kaunas, Lithuania.
Hypercholesterolemia, characterized by elevated levels of low-density lipoprotein cholesterol (LDL-C), along with inflammation, is a well-known risk factor for developing atherosclerosis and coronary artery disease (CAD). Many patients with hypercholesterolemia may carry inherited genetic variants that are not part of the commonly recognized mutations in the , , , and genes. These genetic variants may have cumulative effects that contribute to increased LDL-C levels and CAD development.
View Article and Find Full Text PDFContinuous quality improvement for prehospital STEMI improved triage rates and achievement of gold standard < 90-min EMS-to-balloon time.
Int J Emerg Med
March 2025
Polk County Fire Rescue, Bartow, FL, USA.
Background: ST-elevation myocardial infarction (STEMI) is a type of myocardial infarction caused by a buildup of plaque or clot in the coronary arteries. There are approximately 750,000 STEMI cases each year in the United States. The American Heart Association's Mission Lifeline initiative aimed to optimize prehospital emergency medical services (EMS) and enhance STEMI triage rates through improved standardized protocol.
View Article and Find Full Text PDFImpact of COVID-19 on door-to-wire time in ST-segment elevation myocardial infarction treatment: the role of digital communication.
BMC Cardiovasc Disord
March 2025
Department of Cardiovascular Medicine, Hunan Provincial People's Hospital, Changsha, Hunan, China.
Introduction: ST-segment elevation myocardial infarction (STEMI) is a life-threatening cardiovascular emergency necessitating rapid reperfusion. During the COVID-19 pandemic, healthcare providers faced the challenge of ensuring timely STEMI interventions while managing the risk of viral transmission in hospitals. This study aims to analyze changes in the door-to-wire (D-to-W) time for STEMI treatment across three pandemic phases-early pre-epidemic phase (Group C), initial lockdown phase (Group A), and intermediate normalization phase (Group B).
View Article and Find Full Text PDFSuccessful resolution of ST-segment elevation by intracoronary nicorandil administration during perfusion balloon inflation.
Cardiovasc Interv Ther
March 2025
Department of Cardiology, NTT Medical Center Tokyo, 5-9-22 Higashi-Gotanda, Shinagawa City, Tokyo, 141-8625, Japan.
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