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Aim: In 2017, the American College of Cardiology (ACC) re-defined hypertension (HT) as follows: elevated blood pressure (EBP), systolic blood pressure (SBP) 120-129 mmHg and diastolic blood pressure (DBP) <80 mmHg; stage 1 HT, SBP 130-139 mmHg or DBP 80-89 mmHg; and stage 2 HT: SBP ≥140 mmHg or DBP ≥90 mmHg. It is well known that women with stage 2 HT are at higher risk of preeclampsia and have poorer pregnancy and delivery outcomes. While there are few reports on the risk in women with EBP and stage 1 HT, and none from Japan.

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#Preeclampsiasurvivor and symbolic interactionism in women's maternal health.

Health Care Women Int

July 2024

Department of Electrical Engineering and Computer Science, Howard University, Washington, DC, USA.

A hypertensive disorder of pregnancy and leading cause of maternal mortality worldwide, preeclampsia (PE) impacts approximately one in 25 pregnancies. Biomedical researchers continue to look for concrete causes and effective treatments for PE, but the experience of PE-the personal and socially constructed meanings surrounding the condition-remains under-researched. Using a symbolic interactionism approach, we examined Instagram posts accompanying the #preeclampsiasurvivor hashtag during Preeclampsia Awareness Month.

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Background: Thrombomodulin (TM) is a transmembrane glycoprotein expressed on the endothelial cell functioning as a cofactor in the anticoagulation system. However, aside from anticoagulation, recent studies have revealed its multiple organ protective roles such as anti-inflammation, angiogenesis, and cell proliferation, which may redefine the function of TM. Although TM is predominantly expressed on placental trophoblasts, the physiological role of TM during pregnancy remains unclear.

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Article Synopsis
  • Hypertension was redefined in 2017 with lower standards; elevated blood pressure is now defined as 120-129 mm Hg systolic and stage 1 hypertension as 130-139 mm Hg systolic or 80-89 mm Hg diastolic, but these guidelines didn't address pregnant women.
  • The study aimed to investigate if the newly defined elevated blood pressure and stage 1 hypertension increase the risk of pregnancy complications, including hypertensive disorders and adverse outcomes for mothers and infants.
  • Conducted with 18,801 women from 2013 to 2019, the retrospective study categorized participants based on their blood pressure readings before 20 weeks of gestation and analyzed the association of stage 1 hypertension with pregnancy risks
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