[Drug abuse of pregabalin - state of the situation, risks and means of control].

Ann Pharm Fr

Centre d'assistance médicale urgente et de réanimation (CAMUR), laboratoire de toxicologie, Montfleury, avenue avicenne, 1007 Tunis, Tunisie; Faculté de pharmacie de Monastir (FPHM), rue Ibn Sina, 5000 Monastir, Tunisie; Laboratoire de recherche toxicologique et environnement (LR12SP07), Montfleury, 1007 Tunis, Tunisie.

Published: May 2023

Pregabalin is an anticonvulsant widely used for the treatment of epilepsy and neuropathic pain. However, there is a growing concern about its misuse, particularly among drug users and patients with substance use disorders (SUD). It is often used in combination with other psychoactive molecules and at levels well above the recommended doses. Increasing cases of overdose and death associated with the misuse of pregabalin have been reported worldwide. Therefore, raising prescribers' awareness of this scourge is mandatory and the role of the pharmacist is crucial in reducing this phenomenon.

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Source
http://dx.doi.org/10.1016/j.pharma.2022.11.005DOI Listing

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