Rib Osteomyelitis in Pediatric Patients-Case Series and Literature Review.

Pediatr Infect Dis J

Department of Pediatric Infectious Disease Unit, Dana-Dwek Children's Hospital, Tel Aviv, Israel.

Published: December 2022

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http://dx.doi.org/10.1097/INF.0000000000003712DOI Listing

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Article Synopsis
  • Chronic nonbacterial osteomyelitis (CNO) is an autoinflammatory bone disease primarily found in children and adolescents, and sacroiliitis is an inflammatory condition of the sacroiliac joint diagnosed via MRI.
  • A case study details a 17.5-year-old female patient with classical Ehlers-Danlos syndrome (EDS) who experienced joint pain, hypermobility, and morning stiffness, leading to the diagnosis of CNO and sacroiliitis after a whole-body MRI revealed inflammation.
  • The patient was successfully treated with a combination of medications including risedronate sodium and methotrexate, achieving remission, highlighting the importance of interdisciplinary cooperation for managing the overlapping conditions.
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Introduction: is a bacteria that can be found in normal oral and gastrointestinal flora. infection is rare in immunocompetent patients but is known to cause periorbital cellulitis, endocarditis, osteomyelitis and bacteremia; however, its association with acute respiratory distress syndrome (ARDS) has not been previously documented.

Case Presentation: A 36-year-old female with no known history who presented with right-sided chest, flank and upper abdominal pain after a motor vehicle accident.

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More frequent among adults, phenocopies may be caused by somatic mutations or anti-cytokine autoantibodies, mimicking the phenotypes of primary immunodeficiencies. A fourteen-year-old girl was referred for a two-year history of weight loss and multiple recurrent abscesses, complicated recurrent pneumonia, pyelonephritis, osteomyelitis, and septic shock, without fever. She had started with nausea, hyporexia, and weight loss, then with abscesses in her hands, knee, ankle, and spleen.

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Introduction: Chronic osteomyelitis of the ribs in adolescents and adults is a rare condition. Current understanding of its diagnosis and management is primarily derived from case reports and small series studies. Here, we present a case of chronic rib osteomyelitis initially managed conservatively with antibiotics, followed by debridement, sequestrectomy, and continued antibiotic therapy.

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