Trends in extreme 100-y events of temperature and rainfall amounts in the continental United States are estimated, to see effects of climate change. This is a nontrivial statistical problem because climate change effects have to be extracted from "noisy" weather data within a limited time range. We use nonparametric Bayesian methods to estimate the trends of extreme events that have occurred between 1979 and 2019, based on data for temperature and rainfall. We focus on 100-y events for each month in [Formula: see text] geographical areas looking at hourly temperature and 5-d cumulative rainfall. Distribution tail models are constructed using extreme value theory (EVT) and data on 33-y events. This work shows it is possible to aggregate data from spatial points in diverse climate zones for a given month and fit an EVT model with the same parameters. This surprising result means there are enough extreme event data to see the trends in the 41-y record for each calendar month. The yearly trends of the risk of a 100-y high-temperature event show an average 2.1-fold increase over the last 41 y of data across all months, with a 2.6-fold increase for the months of July through October. The risk of high rainfall extremes increases in December and January 1.4-fold, but declines by 22% for the spring and summer months.
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http://dx.doi.org/10.1073/pnas.2207536119 | DOI Listing |
Sci Rep
December 2024
Civil and Environmental Engineering Department, King Fahd University of Petroleum & Minerals, Dhahran, 31261, Saudi Arabia.
Air pollution monitoring and modeling are the most important focus of climate and environment decision-making organizations. The development of new methods for air quality prediction is one of the best strategies for understanding weather contamination. In this research, different air quality parameters were forecasted, including Carbon Monoxide (CO), Nitrogen Monoxide (NO), Nitrogen Dioxide (NO), Ozone (O), Sulphur Dioxide (SO), Fine Particles Matter (PM), Coarse Particles Matter (PM), and Ammonia (NH).
View Article and Find Full Text PDFArtif Organs
December 2024
Department of Surgical Intensive Care Unit (SICU), The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Objective: To explore the experience of extracorporeal life support (ECLS)-assisted maintenance of brain death donors with extremely unstable hemodynamics.
Methods: We retrospectively analyzed the clinical data of 12 brain-dead donors who received ECLS in our hospital from May 2015 to May 2022 due to extremely unstable hemodynamics. The organ acquisition status was analyzed.
Ying Yong Sheng Tai Xue Bao
October 2024
Changchun Urban Planning and Research Center/Changchun Institute of Urban Planning and Design, Changchun 130028, China.
Jilin Province is an important ecological security barrier in Northeast China as it is located at the junction of the Northeast forest belts and the northern sand prevention belts. In recent years, Jilin Province has actively carried out ecological protection and restoration projects, resulting in a continuous improvement trend for the overall ecological environment. However, the evolution patterns and mechanisms of habitat quality are largely unkown.
View Article and Find Full Text PDFDiscov Med
December 2024
Department of Biochemistry and General Chemistry, Medical College of the University of Rzeszów, 35-959 Rzeszów, Poland.
Photodynamic therapy (PDT) is emerging as a promising treatment for many diseases. This non-invasive approach uses photosensitizing agents and light to selectively destroy abnormal cells, providing a valuable alternative to traditional treatments. Scientists are investigating the use of PDT in various areas of the head, and their work is focused on a growing number of new discoveries and methods for treating cancer.
View Article and Find Full Text PDFJ Pain Res
December 2024
Chariton Pharmaceuticals, Cambridge, MA, USA.
To obtain broad regulatory approval for a new analgesic agent in acute postoperative pain, US and European regulatory authorities require pivotal studies in both hard (bony) tissue pain and soft tissue pain. Bunionectomy is by far the most common hard tissue pivotal trial model, in spite of the fact that the model has limited relevance to clinicians prescribing pain drugs (pain from bunionectomy is not extreme or long-lasting, and is adequately treated by existing drugs). The authors outline the experimental characteristics that make bunionectomy an appealing study model for researchers despite its lack of clinical relevance compared to larger surgeries.
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