Generation of Bone Marrow Chimeras.

Methods Mol Biol

Laboratory of Immune Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.

Published: November 2022

Bone marrow chimeras are widely used in immunological studies, to dissect the contributions of hematopoietic and non-hematopoietic cells in immune cell development or functions, to quantify the impact of a given mutation, or in preclinical studies for hematopoietic stem cell transplantation. Here we describe a set of procedures for the generation of bone marrow chimeras.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10795540PMC
http://dx.doi.org/10.1007/978-1-0716-2740-2_9DOI Listing

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