A new α-Tetralone based chalcone compound, (2E)-2-(4-ethoxybenzylidene)-3,4-dihydro-2H-naphthalen-1-one () has been synthesized by Claisen-Schmidt condensation reaction of α-Tetralone () with 4-Ethoxybenzaldehyde () in basic medium. Then it was allowed to grow through slow evaporation solution growth technique. The molecular structure of grown has been systematically characterized by SCXRD, FT-IR, H NMR and C NMR spectroscopic studies. The micro-hardness, thermal (TGA & DTA) and photoluminence studies of the synthesized were also examined. The was screened for its anti-inflammatory, antidiabetic and anti-oxidant activity. It has shown admirable anti-inflammatory and antidiabetic activity. Protein-Ligand interactions of with SARS-CoV-2 main protease (PDB code: ) also performed.
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| http://dx.doi.org/10.1016/j.molstruc.2021.130967 | DOI Listing |
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