Comparison of the inactivation capacity of various UV wavelengths on SARS-CoV-2.

Biochem Biophys Rep

Laboratory of Global Infectious Diseases Control Science, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo, 113-8657, Japan.

Published: December 2022

AI Article Synopsis

  • SARS-CoV-2 caused a global pandemic, and ultraviolet (UV) light is recognized as an effective way to inactivate it.
  • This study compared the effectiveness of different UV wavelengths (222, 254, 265, and 308 nm) on SARS-CoV-2, finding that wavelengths like 222 nm were efficient, while 308 nm was not effective.
  • The findings highlight the significance of UV wavelength selection for applications aimed at inactivating SARS-CoV-2.

Article Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused a worldwide pandemic. Ultraviolet (UV) is regarded as a very powerful tool against SARS-CoV-2. However, the inactivating effects of different UV wavelengths on SARS-CoV-2 under the same conditions have hardly been compared. Here, we showed that SARS-CoV-2 cultured in Dulbecco's modified Eagle's medium and 2% fetal bovine serum was efficiently inactivated by irradiation with 222, 254, and 265 wavelengths UV, but not at 308 nm. In addition, it was revealed that UV absorption by DMEM-2% FBS is very efficient at 222 nm. Our results present potentially important information for selecting the optimum UV wavelength according to the application.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9638801PMC
http://dx.doi.org/10.1016/j.bbrep.2022.101379DOI Listing

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