In recent years, there has been an increased interest in Ti/Sc generators as an onsite source of Sc for medical applications without needing a proximal cyclotron. The relatively short half-life (3.97 hours) and high positron branching ratio (94.3%) of Sc make it a viable candidate for positron emission tomography (PET) imaging. This review discusses current Ti/Sc generator designs, focusing on their chemistry, drawbacks, post-elution processing, and relevant preclinical studies of the Sc for potential PET radiopharmaceuticals.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10375575 | PMC |
| http://dx.doi.org/10.2174/1874471016666221111154424 | DOI Listing |
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