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Down Syndrome in Children: A Primary Immunodeficiency with Immune Dysregulation.
Children (Basel)
October 2024
Student Scientific Society, English Division, Poznań University of Medical Sciences, 61-701 Poznań, Poland.
The multisystemic features of Down syndrome (DS) in children are accompanied by immunodeficiency, making them susceptible to infections and immune dysregulation with autoimmune, allergic, inflammatory, and hematological complications. This study was aimed at a better understanding of the abnormalities within the B and T cell compartments and their correlations with clinical immunophenotypes. Medical records of 35 DS children were retrospectively reviewed, referring to clinical symptomatology including history of infections, immune dysregulation disorders, and humoral and cellular immune response.
View Article and Find Full Text PDFEfficacy Evaluation of Treatment of Psoriasis Via Narrow Band-Ultraviolet Radiation.
J Lasers Med Sci
July 2024
Proteomics Research Center, Faculty of Paramedical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Psoriasis is a common autoimmune skin disease associated with genetically influenced chronic inflammation accompanied by remitting and deteriorating scaly skin. T-cell targeted biologics, IL-17 inhibitors, IL-12/IL-23 inhibitors, TNF-α inhibitors, PDE4 inhibitors, and ultraviolet (UV) radiation are applied to treat psoriasis. Efficacy evaluation of narrow band UVB (NB-UVB) radiation was the aim of this study.
View Article and Find Full Text PDFCopper deficiency myelopathy mimicking cervical spondylitic myelopathy: a systematic review of the literature with case report.
Spine J
November 2024
Department of Neurological Surgery, Vanderbilt University Medical Center, 1500 21st Avenue S, Nashville, TN 37212, USA.
Background And Context: Copper deficiency myelopathy (CDM) is a rare disease that can present with spastic quadriparesis and sensory ataxia. As a result, it can precisely mimic cervical spondylitic myelopathy (CSM). Copper deficiency may be seen following gastric bypass surgery, malabsorption syndromes such as celiac disease, and with excessive exogenous zinc intake.
View Article and Find Full Text PDFGluten-free lentil cakes with optimal technological and nutritional characteristics.
J Sci Food Agric
August 2024
CIDCA - Facultad de Ciencias Exactas (UNLP - CONICET), La Plata, Argentina.
Background: The celiac population usually struggle finding nutritive gluten-free (GF) baked goods. GF foods can be improved using legume flours. Eleven GF cake formulations were elaborated according to different percentages of lentil flour (LF), corn flour (CF) and rice flour (RF) using a simplex lattice design.
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