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Advancement of the Dragon Heart 7-Series for Pediatric Patients With Heart Failure.
Artif Organs
January 2025
BioCirc Research Laboratory, School of Biomedical Engineering, Science, and Health Systems, Drexel University, Philadelphia, Pennsylvania, USA.
Background: Safe and effective pediatric blood pumps continue to lag far behind those developed for adults. To address this growing unmet clinical need, we are developing a hybrid, continuous-flow, magnetically levitated, pediatric total artificial heart (TAH). Our hybrid TAH design, the Dragon Heart (DH), integrates both an axial flow and centrifugal flow blood pump within a single, compact housing.
View Article and Find Full Text PDFClinical Outcomes of Cardiac Transplantation in Heart Failure Patients with Previous Mechanical Cardiocirculatory Support.
J Clin Med
January 2025
Cardiac Surgery Unit, Spedali Civili, University of Brescia, 25124 Brescia, Italy.
Heart failure (HF) remains a significant public health issue, with heart transplantation (HT) being the gold standard treatment for end-stage HF. The increasing use of mechanical circulatory support, particularly left ventricular assist devices (LVADs), as a bridge to transplant (BTT), presents new perspectives for increasingly complex clinical scenarios. This study aimed to compare long-term clinical outcomes in patients in heart failure with reduced ejection fraction (HFrEF) receiving an LVAD as BTT to those undergoing direct-to-transplant (DTT) without mechanical support, focusing on survival and post-transplant complications.
View Article and Find Full Text PDFOptimizing Mechanical Ventilation: A Clinical and Practical Bedside Method for the Identification and Management of Patient-Ventilator Asynchronies in Critical Care.
J Clin Med
January 2025
Department of Critical Care Medicine, Hospital de São Francisco Xavier, Unidade Local de Saúde Lisboa Ocidental (ULSLO), Estrada Forte do Alto Duque, 1449-005 Lisbon, Portugal.
The prompt identification and correction of patient-ventilator asynchronies (PVA) remain a cornerstone for ensuring the quality of respiratory failure treatment and the prevention of further injury to critically ill patients. These disruptions, whether due to over- or under-assistance, have a profound clinical impact not only on the respiratory mechanics and the mortality associated with mechanical ventilation but also on the patient's cardiac output and hemodynamic profile. Strong evidence has demonstrated that these frequently occurring and often underdiagnosed events have significant prognostic value for mechanical ventilation outcomes and are strongly associated with prolonged ICU stays and hospital mortality.
View Article and Find Full Text PDFRobust Multi-Subtype Identification of Breast Cancer Pathological Images Based on a Dual-Branch Frequency Domain Fusion Network.
Sensors (Basel)
January 2025
School of Mechanical and Electrical Engineering, China Jiliang University, Hangzhou 310018, China.
Breast cancer (BC) is one of the most lethal cancers worldwide, and its early diagnosis is critical for improving patient survival rates. However, the extraction of key information from complex medical images and the attainment of high-precision classification present a significant challenge. In the field of signal processing, texture-rich images typically exhibit periodic patterns and structures, which are manifested as significant energy concentrations at specific frequencies in the frequency domain.
View Article and Find Full Text PDFHighly Responsive Robotic Prosthetic Hand Control Considering Electrodynamic Delay.
Sensors (Basel)
December 2024
Department of Robotics and Mechatronics, Tokyo Denki University, Tokyo 120-8551, Japan.
As robots become increasingly integrated into human society, the importance of human-machine interfaces continues to grow. This study proposes a faster and more accurate control system for myoelectric prostheses by considering the Electromechanical Delay (EMD), a key characteristic of Electromyography (EMG) signals. Previous studies have focused on systems designed for wrist movements without attempting implementation.
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