In this paper, we ask one fairly simple question: to what extent can biorobotics be sensibly qualified as science? The answer clearly depends on what 'science' means and whether what is actually done in biorobotics corresponds to this meaning. To respond to this question, we will deploy the distinction between science and so-called technoscience, and isolate different kinds of objects of inquiry in biorobotics research. Capitalising on the distinction between 'proximal' and 'distal' biorobotic hypotheses, we will argue that technoscientific biorobotic studies address proximal hypotheses, whilst scientific biorobotic studies address distal hypotheses. As a result, we argue that bioroboticians can be both considered as scientists and technoscientists and that this is one of the main payoffs of biorobotics. Indeed, technoscientists play an extremely important role in 21st-century culture and in the current critical production of knowledge. Today's world is increasingly technological, or rather, it is a bio-hybrid system in which the biological and the technological are mixed. Therefore, studying the behaviour of robotic systems and the phenomena of animal-robot interaction means analysing, understanding, and shaping our world. Indeed, in the conclusion of the paper, we broadly reflect on the philosophical and disciplinary payoff of seeing biorobotics as a science and/or technoscience for the increasingly bio-hybrid and technical world of the 21st century.
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http://dx.doi.org/10.1088/1748-3190/aca24b | DOI Listing |
J Biomech
January 2025
Biorobotics and Biomechanics Lab, Department of Mechanical Engineering, University of Maine, Orono, 04469, ME, United States of America. Electronic address:
Interlimb coordination can be used as a metric to study the response of the neuromuscular system to mechanical perturbations and behavioral information. Behavioral information providing haptic feedback on thigh angle has been shown to increase stride length and consequently walking speed, but the effect of such feedback on limb coordination has not been determined. The current work investigates the effects of this feedback on lower-limb coordination and examines if such effects are dependent on the age of the walker.
View Article and Find Full Text PDFPLoS Comput Biol
January 2025
Biorobotics Laboratory, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.
This study introduces a novel neuromechanical model employing a detailed spiking neural network to explore the role of axial proprioceptive sensory feedback, namely stretch feedback, in salamander locomotion. Unlike previous studies that often oversimplified the dynamics of the locomotor networks, our model includes detailed simulations of the classes of neurons that are considered responsible for generating movement patterns. The locomotor circuits, modeled as a spiking neural network of adaptive leaky integrate-and-fire neurons, are coupled to a three-dimensional mechanical model of a salamander with realistic physical parameters and simulated muscles.
View Article and Find Full Text PDFUrology
January 2025
S.H. Ho Urology Centre, Department of Surgery, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China.
Objective: To evaluate the impact of Aquablation on circulating tumor cells (CTCs) in men with localized prostate cancer.
Methods: This prospective study included subjects with biopsy-positive mpMRI visible lesions (PIRADS ≥3) who underwent Aquablation. Ten mL blood samples were collected before, during and after the procedure to measure CTC counts using an immunofluorescence assay.
Sci Rep
January 2025
The BioRobotics Institute, Scuola Superiore Sant'Anna, Pontedera, Pisa, Italy.
Millions of individuals surviving a stroke have lifelong gait impairments that reduce their personal independence and quality of life. Reduced walking speed is one of the major problems limiting community mobility and reintegration. Previous studies have shown positive effect of robot-assisted gait training utilizing hip exoskeletons for individuals with gait impairments due to a stroke, leading to increased walking speed in post-treatment compared to pre-treatment assessments.
View Article and Find Full Text PDFWearable Technol
December 2024
Biorobotics Laboratory, EPFL, Lausanne, Vaud, Switzerland.
Neuromuscular controllers (NMCs) offer a promising approach to adaptive and task-invariant control of exoskeletons for walking assistance, leveraging the bioinspired models based on the peripheral nervous system. This article expands on our previous development of a novel structure for NMCs with modifications to the virtual muscle model and reflex modulation strategy. The modifications consist firstly of simplifications to the Hill-type virtual muscle model, resulting in a more straightforward formulation and reduced number of parameters; and second, using a finer division of gait subphases in the reflex modulation state machine, allowing for a higher degree of control over the shape of the assistive profile.
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