Objective: To determine the association between obstructive sleep apnea syndrome (OSAS) and predicted bone mineral density (BMD) in adults presenting for orthodontic treatment.
Methods: This retrospective cross-sectional study included 38 adults divided into OSAS and non-OSAS groups. Using pre-treatment CBCT images, radiographic density (RD) of left and right lateral regions of the 1st cervical vertebrae and dens of the 2nd cervical vertebrae were measured as an indicator for BMD.
Results: When controlling for age, sex, and BMI, the mean RD was significantly lower in the OSAS group compared to the non-OSAS group (left CV1: 36.69 ± 84.50 vs. 81.67 ± 93.25 Hounsfield Units [HU], respectively, = 0.031; right CV1: 30.59 ± 81.18 vs. 74.26 ± 91.81 HU, = 0.045; dens: 159.25 ± 115.96 vs. 223.94 ± 106.09 HU, = 0.038).
Conclusion: Adults with OSAS have lower values for predicted BMD than those without OSAS.
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