Background: Peste des petits ruminants (PPR) is one of the most severe diseases of small ruminants, causing the loss of millions of dollars annually. A cross-sectional study was conducted to determine the seroepidemiology of peste des petits ruminants virus (PPRV) in unvaccinated sheep and goats in selected districts in Northwest Ethiopia.
Objectives: The study was designed to investigate the epidemiology of PPRV in unvaccinated sheep and goats and risk factors in the study areas.
Methods: A multi-stage sampling was used to select study districts, villages and households with a random sampling approach. Study animals (403 sheep and goats) older than 5 months were selected with a systematic random sampling approach. From the animals, blood samples were aseptically collected and PPRV antibodies from the serum were analysed with enzyme-linked immunosorbent assay (ELISA).
Results: The overall seroprevalence of antibodies to PPRV was 32.5% in both species. It was higher in goats with a prevalence of 34.7% than in sheep (28.3%). District, herd size, sex, animal origin and grazing management were significantly associated with seropositivity of animals to PPRV antibodies. If an animal was from the Dangur district, it had 2.6 times higher chance of being positive than in the Dibati district (OR = 2.6, p = 0.01 and 95% CI = 1.2- 5.6). Herd size was also significantly correlated with the seropositivity with (OR = 4, p = 0.001, and 95% CI = 1.8-9). Also, male animals had 1.7 times higher chance of being positive than females. Further, if an animal comes from the market, it has 2.7 times higher chance of being positive compared to animals born and raised on the farm.
Conclusions: The seropositivity indicates that the disease is circulating in the study areas. Hence, preventive approaches, like vaccination campaigns and strict biosecurity measures, are highly advised to avoid the catastrophic impact of the diseases if an outbreak occurs.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10029864 | PMC |
| http://dx.doi.org/10.1002/vms3.994 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Assessment of Vaccination Impact in PPR-Control Program Implemented in Southern States of India: A System Dynamics Model Approach.
Viruses
December 2024
International Livestock Research Institute (ILRI), Block-C, First Floor, NASC Complex, CG Centre, DPS Marg, Pusa, New Delhi 110012, India.
Mass vaccination against peste des petits ruminants (PPR) in two southern states of India, namely Andhra Pradesh and Karnataka, has reduced disease outbreaks significantly. The sporadic outbreaks reported now can be attributed in part to the recurring movement of sheep and goats between these contiguous states. This study assessed the present level of economic burden and impact of vaccination on the local system (one state), considering the exposure from the external system (neighboring state) using a system dynamic (SD) model.
View Article and Find Full Text PDFPeste des petits ruminants: past, present, and future scope.
J Infect Dev Ctries
December 2024
Department of Veterinary Medicine, Faculty of Agriculture and Veterinary Medicine, An-Najah National University, Nablus, Palestine.
Introduction: Peste des petits ruminants (PPR) is a highly contagious and fatal disease affecting small ruminants, particularly goats and sheep, and is caused by Morbillivirus caprinae, a virus in the genus Morbillivirus, family Paramyxoviridae. PPR has significant economic and social impacts, especially in Africa, Asia, and the Middle East, where small ruminants are vital to rural livelihoods and food security. This disease is a priority for global eradication due to its disproportionate impact on low-income farmers and wildlife conservation.
View Article and Find Full Text PDFSeroprevalence of peste des petits ruminants in sheep and goats managed under pastoral and agro-pastoral systems.
J Infect Dev Ctries
December 2024
SACIDS Africa Centre of Excellence for Infectious Diseases, SACIDS Foundation for One Health, Sokoine University of Agriculture (SUA), P.O. Box 3297 Chuo Kikuu, Morogoro, Tanzania.
Introduction: Peste des petits ruminants (PPR) is an infectious disease that imposes substantial economic burdens on small ruminants (SR) production. For Tanzania to develop efficient management and eradication plans, it is essential to comprehend the seroprevalence of PPR designated for global elimination by 2030.
Methodology: This study investigated the prevalence of PPR in animals kept under pastoral and agropastoral communities in Tanzania.
Enzootic Ovine Abortion among small ruminants in Southern Benin.
Vet Ital
January 2025
University Hospital College, University of Ibadan, Nigeria.
The advancement of small ruminant farming in Benin has encountered challenges associated with health issues and agricultural practices. This study aimed to provide the initial documentation of the prevalence of enzootic ovine abortion and evaluate the health status of animals concerning various recurring diseases on traditional small ruminant farms in Benin. In 2023, a semi-structured survey of 450 farms was carried out in two agricultural development centers in Benin.
View Article and Find Full Text PDFInfectious animal diseases represent a major constraint to livestock productivity, food security and wellbeing in many developing countries. To mitigate these impacts, farmers frequently use antimicrobials without professional advice, potentially yielding drug residues in livestock products and the food chain, as well as resistant antimicrobial genes. Recent studies identified Contagious Bovine Pleuropneumonia (CBPP) and Peste des Petits Ruminants (PPR) as the diseases most negatively affecting ruminant livestock productivity and farmers' wellbeing in Ghana.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!