AI Article Synopsis
- Insect-specific viruses (ISVs) are viruses that only replicate in arthropod cells, particularly studied in mosquitoes due to their role in spreading diseases like dengue, Zika, and chikungunya.
- A study conducted in São Paulo, Brazil, collected mosquito eggs from urban parks and used next-generation sequencing to identify and characterize new ISVs.
- This research marks the first detection of a specific ISV in female mosquitoes in Latin America, highlighting the need for more studies on ISVs to understand their impact on arbovirus transmission in the region.
Article Abstract
Insect-specific viruses (ISVs) are viruses that replicate exclusively in arthropod cells. Many ISVs have been studied in mosquitoes as many of them act as vectors for human etiological agents, such as arboviruses. is an important potential vector of several arboviruses in Brazil, such as dengue (DENV), Zika (ZIKV) and chikungunya (CHIKV). The development of next-generation sequencing metagenomics has enabled the discovery and characterization of new ISVs. eggs were collected using oviposition traps placed in two urban parks in the city of São Paulo, Brazil. The females were divided into pools and the genetic material was extracted and processed for sequencing by metagenomics. Complete genomes of ISV were obtained in three of the four pools tested. This is the first detection of ISV in females in Latin America. Further studies on ISVs in are needed to better understand the role of this species in the dynamics of arbovirus transmission in the Americas.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9696862 | PMC |
| http://dx.doi.org/10.3390/v14112341 | DOI Listing |
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