To study the effect of SAP incorporation on the early shrinkage of SAP internally cured concrete with the aim to solve the problems of early shrinkage and cracking of bridge leveling-layer concrete, using the SAP incorporation method as a parameter, the mechanical properties test of internally cured concrete, the shrinkage performance test of ring restraint and the scanning electron microscope observation test were carried out. The effects of the SAP content and incorporation method on the flowability, mechanical properties, shrinkage performance and microstructure of internally cured concrete were analyzed. The experimental results show that when the content of the SAP in concrete is 0.2% of the mass of cementitious materials, it has the least influence on the compressive strength of concrete. The addition of preabsorbed water to the SAP can delay early cement hydration, increase the later cement hydration rate and final hydration degree, and improve the concrete strength. Preabsorbed water mixed with an SAP can effectively improve the shrinkage of concrete, and the shrinkage reduction effect is more obvious than that from the dry addition of the SAP; the early cracking risk of concrete without an SAP is high, and it will crack before day 28. The addition of an SAP can strengthen the microstructure of concrete and improve its density and crack resistance, effectively avoiding concrete cracking. It is recommended that the water-absorbent resin be incorporated in a preabsorbent manner, and the SAP preabsorbent ratio is equal to the maximum water storage rate of the SAP.
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http://dx.doi.org/10.3390/ma15217854 | DOI Listing |
Front Oncol
January 2025
Endocrinology Unit, Garibaldi-Nesima Hospital, Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy.
Background: Multiple endocrine neoplasia type 2 syndrome (MEN2) is a hereditary disease resulting from mutations of the rearranged during transfection (RET) protooncogene subclassified into MEN2A [medullary thyroid carcinoma (MTC), pheochromocytoma, and primary hyperparathyroidism] and MEN2B (MTC, pheochromocytoma, Marfanoid habitus, mucous neuromas, and intestinal ganglioneuromatosis). Prophylactic thyroidectomy is recommended in RET-mutated patients. The age at which it should be performed depends on the type and aggressiveness of the mutation.
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January 2025
Department of Infectious Diseases, Tongji Hospital, Tongji Medical College and State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Disease, Huazhong University of Science and Technology, Wuhan, China.
As new evidence emerges, treatment strategies toward the functional cure of chronic hepatitis B are evolving. In 2019, a panel of national hepatologists published a Consensus Statement on the functional cure of chronic hepatitis B. Currently, an international group of hepatologists has been assembled to evaluate research since the publication of the original consensus, and to collaboratively develop the updated statements.
View Article and Find Full Text PDFHepatology
February 2025
Department of Medicine III, Division of Gastroenterology and Hepatology, Medical University of Vienna, Vienna, Austria.
Background And Aims: Around 750,000 patients per year will be cured of HCV infection until 2030. Those with compensated advanced chronic liver disease remain at risk for hepatic decompensation and de novo HCC. Algorithms have been developed to stratify risk early after cure; however, data on long-term outcomes and the prognostic utility of these risk stratification algorithms at later time points are lacking.
View Article and Find Full Text PDFCureus
December 2024
Endocrine and Diabetes Unit, Universitair Ziekenhuis Brussel (UZ Brussel), Brussels, BEL.
Hyperandrogenism is a highly prevalent and debilitating hormonal disturbance encountered in women presenting with variable phenotypical features. Causes encompass a large spectrum of tumoral and nontumoral etiologies, depending on the patients' age. We report two postmenopausal patients with an unusual etiology of hyperandrogenism.
View Article and Find Full Text PDFmedRxiv
October 2024
Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, Division of Intramural Research, National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, MD, USA.
Six months of chemotherapy using current agents is standard of care for pulmonary, drug-sensitive tuberculosis (TB), even though some are believed to be cured more rapidly and others require longer therapy. Understanding what factors determine the length of treatment required for durable cure in individual patients would allow individualization of treatment durations, provide better clinical tools to determine the of appropriate duration of new regimens, as well as reduce the cost of large Phase III studies to determine the optimal combinations to use in TB control programs. We conducted a randomized clinical trial in South Africa and China that recruited 704 participants with newly diagnosed, drug-sensitive pulmonary tuberculosis and stratified them based on radiographic disease characteristics as assessed by FDG PET/CT scan readers.
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