AI Article Synopsis
- Genotyping of infected animals in South Korea using multispacer sequence typing (MST) and multiple locus variable number tandem repeat analysis (MLVA) was successfully performed for the first time.
- The results indicated that all strains had the same MLVA genotype of 6-13-2-7-9-10 and MST genotype group 61, which match those previously found in Poland.
- The detection of this MLVA type in humans in France raises concerns about the potential for the Korean strain to cause Q fever in humans, highlighting the importance of MST and MLVA in tracking epidemiological relationships across regions.
Article Abstract
Genotyping of using multispacer sequence typing (MST) and multiple locus variable number tandem repeat analysis (MLVA) was conducted from infected animals for the first time in the Republic of Korea. was detected by real-time PCR, and followed by MST and MLVA genotyping. The result showed that detected all had the same MLVA genotype, 6-13-2-7-9-10 for markers MS23-MS24-MS27-MS28-MS33-MS34, respectively, and genotype group 61 for MST. The same genotypes were previously identified in Poland. Importantly, this MLVA type was detected in humans in France, suggesting that the Korean strain can also potentially cause Q fever in humans. MST and MLVA were very useful tools for analyzing the molecular epidemiology of and helpful for interpreting the epidemiological relationship between isolates from domestic and international resources.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9689931 | PMC |
| http://dx.doi.org/10.3390/genes13111927 | DOI Listing |
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