Microwave breast hyperthermia (MH) aims to increase the temperature at the tumor location with minimal change in the healthy tissue. To this end, the specific absorption rate (SAR) inside the breast is optimized. The choice of the MH applicator design is important for a superior energy focus on the target. Although hyperthermia treatment planning (HTP) changes for every patient, the MH applicator is required to be effective for different breast models and tumor types. The linear applicator (LA) is one of the previously proposed applicator designs with linearly arranged antennas; however, it suffers from low focusing ability in certain breast regions due to its unsymmetrical geometrical features. In this paper, we propose to radially adjust the LA to obtain alternative excitation schemes without actually changing the applicator. Antipodal Vivaldi antennas were utilized, and the antenna excitations were optimized with particle swarm optimization (PSO). The comparison of the rotated and the fixed linear applicator, between 12-antenna circular and linear applicators, and finally, between a 24-antenna circular applicator are provided. Within the 12 rotation angles and two target locations that were analyzed, the 135° axially rotated linear applicator gave a 35% to 84% higher target-to-breast SAR ratio (TBRS) and a 21% to 28% higher target-to-breast temperature ratio (TBRT) than the fixed linear applicator. For the deep-seated target, the 135° rotated linear applicator had an 80% higher TBRS and a 59% higher TBRT than the 12-antenna circular applicator, while the results were comparable to the 24-antenna circular applicator.
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http://dx.doi.org/10.3390/diagnostics12112677 | DOI Listing |
Brachytherapy
December 2024
Department of Radiation Oncology, Virginia Commonwealth University, Richmond, VA. Electronic address:
Purpose: The bladder and rectal toxicities in cervical cancer brachytherapy are positively correlated with the DVH parameter: D2cc. This study evaluates the feasibility of knowledge-based planning to predict the D2cc, identify suboptimal plans, and improve the plan quality with Direction Modulated Brachytherapy (DMBT) applicators using knowledge-based planning based on linear relationship between overlap distances and D2cc.
Methods: The overlap volume histogram (OVH) method was used to determine the distances for 2 cm of overlap between the Organs at Risks (OAR) and High-Risk Clinical Target Volume (CTV).
RSC Adv
October 2024
Department of Biotechnology, Manipal Institute of Technology, Manipal Academy of Higher Education Manipal Karnataka 576104 India
Adv Sci (Weinh)
December 2024
Istituto Nazionale di Ricerca Metrologica (INRiM), Strada delle Cacce 91, Torino, 10135, Italy.
Magnetostrictive materials are essential components in sensors, actuators, and energy-storage devices due to their ability to convert mechanical stress into changes in magnetic properties and vice-versa. However, their operation typically requires physical contact to apply stress or relies on magnetic field sources to control magnetic properties. This poses significant limitations to devices miniaturization and their integration into contactless technologies.
View Article and Find Full Text PDFJ Radiat Res
September 2024
Department of Radiology, Graduate School of Medical Science, University of the Ryukyus, 207 Uehara, Nishihara-cho, Nakagami-gun, Okinawa 903-0215, Japan.
Intracavitary brachytherapy with a remote after-loading system (RALS) is performed as a part of radical radiation therapy in cervical cancer. The radiation source is delivered directly through an applicator placed inside the uterus or vagina. Thorough quality control is important to prevent accidents that can lead to serious irradiation error, and an applicator check is one such quality control measure.
View Article and Find Full Text PDFA high-energy electron accelerator is used in the treatment of patients in the so-called intraoperative electron radiotherapy (IOERT). The work aimed to present the results of the validation of a new design of an electron beam applicator for use in IOERT. A novel solution was described along with the design optimization method based on Monte Carlo simulations.
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