AI Article Synopsis
- - Recent research highlights how the body manages inflammation and its implications for treating cardiovascular diseases, particularly atherosclerosis.
- - The review focuses on the emerging role of Specialized Pro-resolving Mediators (SPMs) and their significance in understanding cardiovascular treatment options.
- - The authors anticipate that ongoing research will lead to clinical trials that utilize these findings to treat inflammatory conditions like coronary artery disease and asthma.
Article Abstract
Recent research on how the body resolves this inflammation is gaining traction and has shed light on new avenues for future management of cardiovascular diseases. In this narrative review, we discuss the pathophysiological mechanisms of atherosclerosis, the recent development in the understanding of a new class of molecules called Specialized Pro-resolving Mediators (SPMs), and the impact of such findings in the realm of cardiovascular treatment options. We searched the MEDLINE database restricting ourselves to original research articles as much as possible on the complex pathophysiology of atherosclerosis and the role of SPMs. We expect to see further research in translating these findings to bedside clinical trials in treating conditions with a pathophysiological basis of inflammation, such as coronary artery disease, asthma, and periodontal disease.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9687471 | PMC |
| http://dx.doi.org/10.3390/biomedicines10112829 | DOI Listing |
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