AI Article Synopsis
- Body composition (BC) assessment has gained attention as a tool for evaluating nutritional status, offering insights beyond traditional metrics like BMI and albumin.
- Studies show that different body composition types are linked to varying health outcomes, particularly in patients with conditions like cirrhosis and cancer, where muscle abnormalities can predict higher risks of complications.
- Despite its potential benefits, BC assessment is not routinely included in pre-therapy evaluations due to inconsistent data, a lack of standard methods, and differences in body composition across populations.
Article Abstract
In the last decade, body composition (BC) assessment has emerged as an innovative tool that can offer valuable data concerning nutritional status in addition to the information provided by the classical parameters (i.e., body mass index, albumin). Furthermore, published data have revealed that different types of body composition are associated with different outcomes. For example, abnormalities of skeletal muscle, a common finding in cirrhotic and oncologic patients, are associated with poor outcome (i.e., high morbidity and high mortality). The disposition (visceral/subcutaneous adipose tissue) and radiodensity of adipose tissue proved to also be determinant factors for HCC outcome. Despite all the advantages, BC assessment is not part of the standard pre-therapeutic workup. The main reasons are the high heterogeneity of data, the paucity of prospective studies, the lack of a standard assessment method, and the interpopulation variation of BC. This paper aims to review the available evidence regarding the role of BC as a prognostic tool in the HCC population undergoing various therapies.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9656561 | PMC |
| http://dx.doi.org/10.3390/cancers14215290 | DOI Listing |
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