AI Article Synopsis
- - The incidence of hepatitis C virus (HCV) infections has increased significantly in reproductive-aged adults over the past decade, posing risks for both maternal health and perinatal transmission.
- - Despite the availability of effective curative treatments for HCV, these are not recommended during pregnancy, raising concerns about missed opportunities for timely intervention.
- - A study across four U.S. jurisdictions found that among 1,161 pregnancies from 2018-2021 involving individuals with HCV, a notable percentage had their first HCV detection before pregnancy, suggesting gaps in treatment that could have benefited maternal health and reduced transmission risks.
Article Abstract
The incidence of hepatitis C virus (HCV) infection in reproductive-aged adults quadrupled during the past decade. Hepatitis C can progress to advanced liver disease and be transmitted perinatally. Highly effective curative hepatitis C treatment is available but is not recommended in pregnancy. Using the Surveillance for Emerging Threats to Mothers and Babies Network, we describe timing of positive RNA testing among pregnant people with HCV (HCV RNA detected during or within one year prior to pregnancy). Four US jurisdictions reported 1161 pregnancies during 2018-2021 among people with hepatitis C: 75.9% were multiparous; and 21.4% had their first peri-pregnancy HCV RNA detected prior to pregnancy, indicating potential missed treatment opportunities to improve maternal health and prevent perinatal transmission.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10951865 | PMC |
| http://dx.doi.org/10.1097/AOG.0000000000004980 | DOI Listing |
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