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DEK::AFF2 fusion-associated middle ear non-keratinizing squamous cell carcinoma: A case report.
World J Clin Oncol
December 2024
Department of Pathology, Peking University People's Hospital, Beijing 100044, China.
Background: Primary squamous cell carcinoma (SCC) of the middle ear is rare, with non-keratinizing basaloid types being exceptionally uncommon. Distinguishing these cancers, often caused by viral factors (, human papillomavirus or Epstein-Barr virus), or specific genetic alterations (, bromodomain-containing protein 4-nuclear protein in or gene fused with FLI chromosomal rearrangement), from other cranial conditions, is difficult. The recently identified DEK::AFF2 non-keratinizing SCC (NKSCC) is a novel subtype, fitting the World Health Organization classification of head and neck neoplasms.
View Article and Find Full Text PDFSurgical interventions for spontaneous supratentorial intracerebral haemorrhage: a systematic review and network meta-analysis.
EClinicalMedicine
January 2025
Department of Neurosurgery and Chinese Evidence-Based Medicine Centre and Cochrane China Centre and MAGIC China Centre and IDEAL China Centre, West China Hospital, Sichuan University, Chengdu, China.
Background: Surgical interventions for spontaneous supratentorial intracerebral haemorrhage (ICH) include conventional craniotomy (CC), decompressive craniectomy (DC), and minimally invasive surgery (MIS), with the latter encompassing endoscopic surgery (ES) and minimally invasive puncture surgery (MIPS). However, the superiority of surgery over conservative medical treatment (CMT) and the comparative benefits of different surgical procedures remain unclear. We aimed to evaluate the efficacy and safety of various surgical interventions for treating ICH.
View Article and Find Full Text PDFInvestigation of Antibiotic-Releasing Biodegradable Composite Bone Cements for Treating Experimental Chronic Maxillofacial Bone Infection.
J Biomed Mater Res A
January 2025
Department of Periodontics, Dr. R. Ahmed Dental College and Hospital, Kolkata, West Bengal, India.
Chronic osteomyelitis of the maxillofacial bones (i.e., jaw bones) is a persistent infection that requires effective treatment.
View Article and Find Full Text PDF[Evaluation of the efficacy of 70% ethanol in removing calcium hydroxide in curved root canals].
Shanghai Kou Qiang Yi Xue
October 2024
Department of General Dentistry, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine; College of Stomatology, Shanghai Jiao Tong University; National Center for Stomatology; National Clinical Research Center for Oral Diseases; Shanghai Key Laboratory of Stomatology; Shanghai Research Institute of Stomatology. Shanghai 200011, China. E-mail:
Purpose: To evaluate the efficacy of micro-computed tomography(Micro-CT) in removing calcium hydroxide from posterior curved root canals.
Methods: Twenty molar teeth (48 root canals) extracted at the Department of General Dentistry, Shanghai Ninth People's Hospital between December 2023 and February 2024 were collected. After preparing by Ni-TI instruments M3 according to standard root canal treatment procedures, calcium hydroxide was injected into the root canals.
[Comparative study of iRoot SP and AH Plus on root canal sealing ability in periodontally compromised teeth].
Shanghai Kou Qiang Yi Xue
October 2024
Department of Periodontology, School and Hospital of Stomatology, Cheeloo College of Medicine, Shandong University; Shandong Key Laboratory of Oral Tissue Regeneration; Shandong Engineering Research Center of Dental Materials and Oral Tissue Regeneration; Shandong Provincial Clinical Research Center for Oral Diseases. Jinan 250012, Shandong Province, China. E-mail:
Purpose: This study was aimed to compare the difference between iRoot SP and AH Plus on root canal sealing ability for teeth extracted due to severe periodontitis and explore whether the dentin tubule pathway plays an important role in the development of endodontic-periodontic lesions(EPL), in order to provide a theoretical basis for selection of proper time for root canal therapy and suitable root canal sealants in patients with EPL.
Methods: Fifty single-root anterior teeth extracted due to severe periodontitis were selected. The roots were completely debrided to remove the calculus, dental plaque and cementum.
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