Diffuse Large B-Cell Lymphoma (DLBCL) in an Aged Raccoon ().

Vet Sci

Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna, Via A. Bianchi 9, 25124 Brescia, Italy.

Published: November 2022

A 15-years-old, captive, female raccoon () was necropsied after a one-week history of apathy and self-isolation. Gross changes consisted of the severe enlargement of the mesenteric lymph node; hepatosplenomegaly with multifocal to coalescing, white tan nodules in the spleen and liver,; and pale kidneys. Histologically, neoplastic CD79α-positive lymphocytes effaced the mesenteric lymph node and multifocally infiltrated the spleen, liver, and kidneys, and focally infiltrated the heart. Based on pathological and immunohistochemical findings, as well as the canine-adapted World Health Organization (WHO) diagnostic criteria, a diagnosis of diffuse large B-cell lymphoma (DLBCL) was made.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9696560PMC
http://dx.doi.org/10.3390/vetsci9110611DOI Listing

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