In this present work, we demonstrate an efficient electrochemical sensor for the detection of hydrogen peroxide (HO) using a glassy carbon electrode (GCE) modified with a ternary nanocomposite of tin oxide QDs/GO/PPy (SGP2). An in situ chemical oxidative polymerization method was used to create the SGP2 nanocomposite. FTIR, XRD, HR TEM, CV, DPV, and impedance analysis were used to characterize the nanocomposite. The SGP2 nanocomposite modified GCE can be used to create an effective HO electrochemical sensor with high sensitivity and a low detection limit (LOD). With SGP2 modified GCE, the electrochemical detection test for HO was carried out using cyclic voltammetry (CV) and amperometric methods. The SGP2 modified GCE shows improved sensing capabilities, resulting in considerable sensitivity of 11.69 µA mM cm and a very low limit of detection (LOD) of 0.758 µM for a broad linear range of HO concentration from 0.1 mM to 0.8 mM with a correlation coefficient R = 0.9886. Additionally, the performance of the SGP2-modified GCE electrode is on par with or nonetheless superior to that of the other functional materials that have been reported for HO. As a result, our findings suggest that combining conductive polymer with metal oxide may be a useful method for producing sophisticated and affordable electrochemical sensors.
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http://dx.doi.org/10.3390/bios12110983 | DOI Listing |
Heliyon
January 2025
Environmental Health Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Iran.
In this study, a Cu@Ag core-shell was synthesized using a co-precipitation method. To create a new electrochemical sensor, a Cu@Ag core-shell with conductive polymers such as polyalizarin yellow R (PA) and Nafion (Nf) was immobilized on the surface of a glassy carbon electrode (Cu@Ag-Nf/PA/GCE). X-ray diffraction analysis (XRD), energy dispersive X-ray analysis (EDX), transmission electron microscopy (TEM), and Fourier Transform Infrared Spectroscopy (FTIR) techniques were employed to characterize the Cu@Ag-Nf/PA/GCE.
View Article and Find Full Text PDFLangmuir
January 2025
Department of Chemistry, School of Applied Sciences, REVA University, Bengaluru 560064, Karnataka, India.
Promethazine hydrochloride (PMHC) is a vital drug that is used as an anticholinergic, antipsychotic, antihistaminic, analgesic, sedative, and neuroleptic. However, the overdosage of PMHC also causes reproductive variations, cardiac changes, hypotension, and endocrinal variations. Hence, the detection of PMHC is crucial.
View Article and Find Full Text PDFLangmuir
January 2025
Department of Chemistry, SRM Institute of Science and Technology, Kattankulathur 603203, Tamil Nadu India.
5-Fluorouracil (5-Fu) is the third-most often used chemotherapeutic medication and has been scientifically demonstrated to be effective in treating solid tumors, including colorectal, stomach, cutaneous, and breast cancers. When used in excess, it accumulates toxic metabolites, which can have deadly and very harmful effects on people, including neurotoxicity and the induction of morbidity. Therefore, sensitive and rapid analytical techniques for detecting 5-Fu in human blood serum are needed to enhance chemotherapy and forecast the possible adverse effects of 5-Fu residues in the human body.
View Article and Find Full Text PDFFood Chem X
January 2025
Hunan Key Laboratory of Biomedical Nanomaterials and Devices, College of Life Science and Chemistry, Hunan University of Technology, Zhuzhou 412007, China.
An ultrasensitive and selective voltammetric platform combined a molecularly imprinted poly(pyrrole) membrane with Ag-nanoparticle-functionalized black phosphorus nanosheets (MIP/BPNS-AgNPs) was developed for trace GAT detection. The physicochemical properties of the MIP/BPNS-AgNPs were studied by various spectroscopic and electrochemical techniques. BPNS-AgNPs improved the ambient stability and electrochemical activity of the BPNS and possessed a large surface area for accommodating abundant templates to produce specific imprinted sites.
View Article and Find Full Text PDFInt J Biol Macromol
January 2025
College of Chemistry and Chemical Engineering, Southwest Petroleum University, Chengdu 610500, PR China; Engineering Research Center of Oilfield Chemistry, Ministry of Education, Chengdu 610500, PR China; Oil & Gas Field Applied Chemistry Key Laboratory of Sichuan Province, Chengdu 610500, PR China. Electronic address:
In this study, polyamide/silica/sodium alginate (SA) composite (PA-Si-SA) was successfully prepared in one-step benzoxazine-isocyanide chemistry (BIC)/sol-gel process at room temperature. The chemical structure and fundamental properties of PA-Si-SA were characterized by FT-IR, solid-state C NMR, XPS, XRD, SEM, BET and TG, etc. The presence of anionic SA and diverse N, O-containing functional segments (amide, tertiary amine, alkyl/phenol -OH, Si-O-Si, and COO) in PA-Si-SA endows it synergistic complexation capability toward Pb and Cd.
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