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| http://dx.doi.org/10.1007/s00277-022-05020-5 | DOI Listing |
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Utilization of High-Flow Nasal Cannulas in Pediatric Critical Care: A Single-Center Experience.
Cureus
December 2024
Pediatric Intensive Care Unit, King Fahad Medical City, Riyadh, SAU.
Background: High-flow nasal cannula (HFNC) therapy has developed as a valuable tool for respiratory support in pediatric critical care. It offers an intermediate level of support between traditional low-flow oxygen and non-invasive ventilation (NIV). Studies suggest its effectiveness in improving oxygen delivery, work of breathing, and secretion clearance.
View Article and Find Full Text PDFSerial biomarker measurements may be helpful to predict the successful application of high flow nasal cannula in COVID-19 pneumonia patients.
Sci Rep
January 2025
The Queen's Medical Center, 1301 Punchbowl Street, QET 4M, Honolulu, Hawai'i, 96813, USA.
High flow nasal cannula (HFNC) can reduce the need for intubation in patients with coronavirus disease-19 (COVID-19) pneumonia induced acute hypoxemic respiratory failure (AHRF), but predictors of HFNC success could be characterized better. C-reactive protein (CRP) and D-dimer are associated with COVID-19 severity and progression. However, no one has evaluated the use of serial CRP and D-dimer ratios to predict HFNC success.
View Article and Find Full Text PDFEffect of Flow Rates of High-flow Nasal Cannula on Extubation Outcomes: A Randomized Controlled Trial.
Chest
December 2024
From the Division of Pulmonary and Critical Care Medicine, National Taiwan University Hospital, Taipei, Taiwan. Electronic address:
Background: High-flow nasal cannula (HFNC) has emerged as a promising intervention for post-extubation oxygen therapy, with the potential to reduce the need for reintubation. However, it remains unclear whether using a higher flow setting provides better outcomes than the commonly used flow rate of 30-50 L/min.
Research Question: Does setting the flow rate of HFNC at 60 L/min versus 40 L/min for post-extubation care result in different extubation outcomes?
Study Design And Methods: This randomized controlled trial assigned intubated patients to receive HFNC at either a 60 L/min or 40 L/min flow rate following extubation.
Impact of 30 mL/kg fluid resuscitation completed within one hour on elderly septic shock patient.
Ann Med
December 2025
Department of Emergency, Changzhou No.2 People's Hospital, Changzhou City, Jiangsu Province, China.
Objective: This study aimed to investigate the prognostic impact of completing 30 mL/kg fluid resuscitation within 1 h in elderly septic shock patients.
Methods: This was a multicenter prospective observational cohort study. We applied logistic regression to assess the impact of completing 30 mL/kg fluid resuscitation within 1 h on respiratory support escalation including new-onset mechanical ventilation, bilevel positive airway pressure (BiPAP), and high-flow nasal cannula (HFNC) as well as heart failure (HF).
Indications and outcomes of pediatric high flow nasal cannula use in the home setting.
J Hosp Med
December 2024
Complex Care Program, Department of Paediatrics, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.
Objective: To describe the patient characteristics, indications, and clinical outcomes of home high flow nasal cannula (HFNC) among pediatric patients. To evaluate secular trends in home HFNC initiation between 2013 and 2022.
Methods: A retrospective review of all children on home HFNC between 2013 and 2023 was conducted at a tertiary care pediatric hospital in Ontario, Canada.
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