AI Article Synopsis
- As living standards rise, obesity rates are increasing, leading to more cases of gastroesophageal reflux disease (GERD).
- Esophageal multichannel intraluminal impedance pH monitoring is a key diagnostic tool for GERD using various parameters, and recent studies are focusing on mean nocturnal baseline impedance (MNBI) and post-reflux swallow-induced peristaltic wave (PSPW) index as new metrics.
- MNBI and PSPW index are showing promise in enhancing the diagnostic accuracy and predicting treatment outcomes for GERD patients.
Article Abstract
Background: As living standards improve, more and more people are becoming overweight or obese, which has led to a gradual increase in the incidence of gastroesophageal reflux disease (GERD). Esophageal multichannel intraluminal impedance pH monitoring is a technique widely used in the clinical diagnosis of GERD. Commonly used traditional impedance parameters include acid exposure time, number of reflux episodes, symptom association probability, and symptom index. Recently, mean nocturnal baseline impedance (MNBI) and post-reflux swallow-induced peristaltic wave (PSPW) index have been proposed as novel impedance parameters to evaluate esophageal mucosal integrity and esophageal chemical clearance, respectively. It was also pointed out that the MNBI and PSPW index can improve the diagnostic value of impedance pH monitoring and predict the treatment outcome of GERD.
Summary: MNBI and PSPW index are objective and reliable novel impedance parameters with high applicability and reproducibility, which are able to improve the diagnostic yield of impedance pH monitoring and predict treatment outcomes in GERD patients.
Key Messages: In this paper, we mainly review the research progress of the MNBI and the PSPW index in the diagnosis and treatment of GERD.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1159/000527867 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Pacing and Ablation Technique Using Microelectrode for Pulmonary Vein Isolation Using a Local Impedance-Guided Catheter.
Pacing Clin Electrophysiol
January 2025
Department of Cardiology, Saitama Medical University, International Medical Center, Hidaka, Saitama, Japan.
Background: The IntellaNav MiFi OI catheter (MiFi) is equipped with a sensor for local impedance (LI) monitoring and three mini-electrodes. In this study, we investigated the target LI values for a successful pulmonary vein isolation (PVI) under the pacing and ablation technique using the MiFi catheter.
Methods: Twenty-seven patients underwent PVI using the MiFi catheter under mini electrode pacing from the MiFi catheter.
Real-Time Monitoring of Electrode Surface Changes in Fast-Scan Cyclic Voltammetry Using Fourier Transform Electrochemical Impedance Spectroscopy.
ACS Omega
January 2025
Department of Biomedical Engineering, Hanyang University, Seoul 04763, Republic of Korea.
Fast-scan cyclic voltammetry (FSCV) is a widely used electrochemical technique to measure the phasic response of neurotransmitters in the brain. It has the advantage of reducing tissue damage to the brain due to the use of carbon fiber microelectrodes as well as having a high temporal resolution (10 Hz) sufficient to monitor neurotransmitter release in vivo. During the FSCV experiment, the surface of the carbon fiber microelectrode is inevitably changed by the fouling effect.
View Article and Find Full Text PDFProgressive Approaches in Oncological Diagnosis and Surveillance: Real-Time Impedance-Based Techniques and Advanced Algorithms.
Bioelectromagnetics
January 2025
Micropropulsion and Nanotechnology Laboratory, School of Engineering and Applied Science, George Washington University, Washington, DC, USA.
Cancer remains a formidable global health challenge, necessitating the development of innovative diagnostic techniques capable of early detection and differentiation of tumor/cancerous cells from their healthy counterparts. This review focuses on the confluence of advanced computational algorithms with noninvasive, label-free impedance-based biophysical methodologies-techniques that assess biological processes directly without the need for external markers or dyes. This review elucidates a diverse array of state-of-the-art impedance-based technologies, illuminating distinct electrical signatures inherent to cancer vs healthy tissues.
View Article and Find Full Text PDFMucosal integrity and acid sensitivity predict proton pump inhibitor response in patients with heartburn and normal acid exposure.
Dig Liver Dis
January 2025
Department of Medicine, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation and Tzu Chi University, Hualien, Taiwan; Institute of Medical Sciences, Tzu Chi University, Hualien, Taiwan. Electronic address:
Background: Patients with typical reflux symptoms and normal acid exposure time (AET) are classified as either reflux hypersensitivity (RH) or functional heartburn (FH), some of whom respond to proton pump inhibitors (PPIs). We determined if esophageal psychophysiological parameters predict PPI response in symptomatic RH and FH patients.
Methods: We prospectively recruited adults with heartburn diagnosed with RH or FH on 24-h impedance-pH monitoring off PPI.
Clinical Importance of Tissue Proximity Indication During Pulsed Field Ablation for Atrial Fibrillation: Insights from Initial Experience.
Heart Rhythm
January 2025
Division of Cardiology, Department of Medicine, Nihon University School of Medicine Tokyo Japan. Electronic address:
Background: Pulsed field ablation (PFA) for paroxysmal atrial fibrillation (AF) has been gaining worldwide acceptance due to its efficacy and safety. A variable loop circular catheter (VLCC, VARIPULSE, Biosense Webster, Inc.) for PFA, recently launched in Japan, includes a Tissue Proximity Indication (TPI) feature to monitor catheter-tissue contact via impedance.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!