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Nat Biotechnol
November 2022
Benjamin N. Cardozo School of Law, New York, NY, USA.
Serum polyamine metabolic profile in autoimmune thyroid disease patients.
Clin Endocrinol (Oxf)
May 2019
Department of Endocrinology and Metabolism, Institute of Endocrinology, Liaoning Provincial Key Laboratory of Endocrine Diseases, The First Hospital of China Medical University, China Medical University, Shenyang, China.
Objective: Polyamines are indispensable polycations and play important physiological roles in living cells. Some polyamine metabolites have been associated with autoimmune disorders. The aims of this study were to profile polyamine metabolites in autoimmune thyroid disease (AITD) and predict whether polyamine metabolites are associated with thyroid hormone, thyroid autoantibodies or disease progression.
View Article and Find Full Text PDFDetection of Angiotensin II type I-receptor antibodies in transplant glomerulopathy.
Clin Transplant
November 2018
Renal Transplantation Center, "A. Vercellone", Division of Nephrology Dialysis and Transplantation, Città della Salute e della Scienza Hospital and Department of Medical Sciences, University of Turin, Turin, Italy.
Background: Transplant glomerulopathy (TG) is an important cause of late graft loss. The role of angiotensin type 1-receptor antibodies (AT R-Ab) in TG is not known.
Methods: All the TG cases (N = 137) between January 2007 and December 2014 (N = 1410) were analyzed.
An addressable packing parameter approach for reversibly tuning the assembly of oligo(aniline)-based supra-amphiphiles.
Chem Sci
May 2018
School of Chemistry , University of Bristol, Bristol , BS8 1TS , UK . Email:
We present a newly developed approach to non-covalently address the packing parameter of an electroactive amphiphile. The pH-responsive reversible switching of a tetra(aniline)-based cationic amphiphile, -pentyl trimethylammonium bromide (), between self-assembled vesicles and nanowires by acid/base chemistry in aqueous solution is used to exemplify this approach. Trifluoroacetic acid () was selected as a prototypical acid to form emeraldine salt (ES) state () vesicles for this new class of small-molecule supramolecular amphiphiles.
View Article and Find Full Text PDFPtaB, a lim-domain binding protein in Aspergillus fumigatus regulates biofilm formation and conidiation through distinct pathways.
Cell Microbiol
January 2018
Departments of Medicine and of Microbiology and Immunology, McGill University, Montreal, Canada.
The exopolysaccharide galactosaminogalactan (GAG) plays an important role in mediating adhesion, biofilm formation, and virulence in the pathogenic fungus Aspergillus fumigatus. The developmental modifiers MedA, StuA, and SomA regulate GAG biosynthesis, but the mechanisms underlying this regulation are poorly understood. PtaB is a lim-domain binding protein that interacts with the transcription factor SomA and is required for normal conidiation and biofilm formation.
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