AI Article Synopsis
- The study aimed to analyze epidemiological trends and mortality rates of cutaneous lupus erythematosus (CLE) in Olmsted County, Minnesota, over a 42-year period from 1976 to 2018.
- Researchers used medical records to identify and categorize CLE cases among local adults and found a consistent incidence rate of 3.9 per 100,000 people without significant variations across age or gender.
- The mortality rate of CLE patients was found to be similar to the general population, with no significant changes observed over the study period.
Article Abstract
Objective: To characterize the epidemiological trends and mortality of cutaneous lupus erythematosus (CLE) between 1976 and 2018 in Olmsted County, Minnesota.
Patients And Methods: In this retrospective population-based cohort study, all incident and prevalent CLE cases among adult residents in Olmsted County, Minnesota, between January 1, 1976, and December 31, 2018, were identified and categorized by subtype through medical record review using the resources of the Rochester Epidemiology Project.
Results: The overall incidence rate of CLE between 1976 and 2018 was 3.9 (95% CI, 3.4 to 4.5) per 100,000. The incidence of CLE was relatively stable, with no major trend across sexes or age groups. The age- and sex-adjusted prevalence of CLE was 108.9 per 100,000 on January 1, 2015. Mortality in CLE patients was similar to that of the general population, with a standardized mortality ratio of 1.23 (95% CI, 0.88 to 1.66) with no observed trends in mortality over time.
Conclusion: In the past 4 decades, the incidence of CLE remained stable. Patients with CLE have mortality comparable to that of the general population.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10013735 | PMC |
| http://dx.doi.org/10.1016/j.mayocp.2022.06.022 | DOI Listing |
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