Although airborne urban particles are a concern for air quality and human health, little information exists on the levels and characteristics of microplastics (MPs) and microrubbers (MRs) in this setting. In the present study, MPs and MRs are quantified and characterised in road dusts and accumulations captured passively (and up to elevations of 177 cm above road level) in the steps of utility poles at 18 locations throughout the city of Shiraz, southwest Iran. Dust accumulation rates were greatest at road level (median = 45 g m month) and declined with elevation (median = 2.0 g m month at 177 cm). The accumulation rates and concentrations (per g of dust) of MPs and MRs were more variable between locations but accumulation declined with elevation for both particle types and MR concentration (up to ∼27,000 MR g) was always greater than corresponding MP concentration (up to ∼3300 MP g). Increasing elevation was also accompanied by an increasing proportion of fine (≤100 μm) and fibrous particles, and in particular for MPs. Fractionation in the quantities and characteristics with elevation above road level are attributed to the extent of resuspension of MPs and MRs from the road surface by wind and passing traffic, with aerodynamic considerations predicting the greatest and most widespread resuspension of fibrous MPs. The fractionation of MPs and MRs with elevation above road level also results in different exposures for adults and children.
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http://dx.doi.org/10.1016/j.envpol.2022.120575 | DOI Listing |
Glob Health Res Policy
January 2025
Center for Public Health and Epidemic Preparedness and Response, Peking University, Haidian District, 38Th Xueyuan Road, Beijing, 100191, China.
Background: As population aging intensifies, it becomes increasingly important to elucidate the casual relationship between aging and changes in population health. Therefore, our study proposed to develop a systematic attribution framework to comprehensively evaluate the health impacts of population aging.
Methods: We used health-adjusted life expectancy (HALE) to measure quality of life and disability-adjusted life years (DALY) to quantify the burden of disease for the population of Guangzhou.
Inj Epidemiol
January 2025
Injury Prevention Research Center, University of Iowa, 145 N Riverside Dr., Iowa City, IA, 52242, USA.
Background: Motor vehicle crashes are the second leading cause of injury death among adults aged 65 and older in the U.S., second only to falls.
View Article and Find Full Text PDFEur J Med Res
January 2025
Department of Nephrology, Affiliated Hospital of Jiaxing University (The First Hospital of Jiaxing), No.1882, Zhonghuan North Road, Jiaxing, 314000, Zhejiang, China.
Background: Dysfunction in podocyte mitophagy has been identified as a contributing factor to the onset and progression of diabetic nephropathy (DN), and BMAL1 plays an important role in the regulation of mitophagy. Thus, this study intended to examine the impact of BMAL1 on podocyte mitophagy in DN and elucidate its underlying mechanisms.
Materials And Methods: High D-glucose (HG)-treated MPC5 cells was used as a podocyte injury model for investigating the potential roles of BMAL1 in DN.
BMC Ophthalmol
January 2025
Department of Ophthalmology, Eye & ENT Hospital, Fudan University, 83 Fenyang Road, Xuhui District, Shanghai, 200031, China.
Background: To investigate the impact of central corneal astigmatism on postoperative visual outcomes in patients with trifocal intraocular lens (IOL) implantation.
Methods: This retrospective study included 278 eyes of 278 patients who underwent uneventful cataract surgery with implantation of the trifocal IOL (AT LISA tri 839MP). Patients were divided into two groups according to the total corneal refractive power (TCRP) in 3 mm zone centered on the corneal apex: low astigmatism group, TCRP ≤ 0.
J Transl Med
January 2025
Department of General Surgery, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, No.1, Minde Road, Nanchang, 330006, Jiangxi, China.
Background: HCC is characterized by a high interstitial fluid pressure (HIFP) environment, which appears to support cancer cell survival. However, the mechanisms behind this phenomenon are not fully understood.
Methods: This study investigates the role of kinesin family member 11 (KIF11) in HCC under HIFP conditions, using both in vivo and in vitro models.
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