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A 42-year-old man with nodular skin lesions. | LitMetric

A 42-year-old man with nodular skin lesions.

J Assoc Med Microbiol Infect Dis Can

Department of Internal Medicine, Section of Infectious Diseases, Max Rady College of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.

Published: June 2021

AI Article Synopsis

Article Abstract

Nodular skin lesions are infrequently reported among patients with syphilis. We describe a 42-year-old man with secondary syphilis who presented with a nodular cutaneous eruption involving his neck, upper chest, back, arms, and legs. Because there was uncertainty regarding the diagnosis at presentation, the patient underwent a punch biopsy of one of the lesions. Spirochetes were not seen with a Steiner silver stain, but they were visualized on subsequent immunohistochemical staining. The diagnosis was confirmed with serology, and the patient responded well to treatment with benzathine penicillin G. Given the current increase in syphilis cases across North America, it is critical that clinicians become familiar with some of the less common dermatologic manifestations of this infection so that the diagnosis is entertained and appropriate serologic testing is ordered in a timely fashion.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9608693PMC
http://dx.doi.org/10.3138/jammi-2020-0051DOI Listing

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