AI Article Synopsis
- The study investigates how smoking affects eye health by comparing osmolarity scores in smokers and non-smokers using two measurement systems, TearLab and I-Pen.
- Thirty male smokers and a matching control group of non-smokers participated, with results showing smokers had higher ocular surface disease index (OSDI) and osmolarity scores.
- The findings reveal a strong correlation between TearLab and I-Pen scores in smokers, with both systems indicating significantly poorer eye health compared to non-smokers.
Article Abstract
Purpose: Smoking has a negative effect on health and ocular tear film. The purpose of the current study is to investigate the correlation between the TearLab and I-Pen osmolarity scores in smokers and compare them with those of non-smoking healthy males.
Methods: Thirty male smokers (25.3 ± 2.2 years) participated in the study. An age-matched (22.9 ± 2.0 years) control group of non-smoking healthy males ( = 30) was also recruited for comparison purposes. The ocular surface disease index (OSDI) was completed first, followed by the TearLab and I-Pen osmolarity measurements.
Results: The median TearLab osmolarity score was lower ( < 0.001) than that obtained using the I-Pen in both the study and the control groups. The OSDI scores and osmolality measurements were higher ( < 0.001) in smokers than in the control subjects. In the smoker group, there were moderate correlations between the OSDI scores and the measurements obtained using the TearLab (Spearman's correlation coefficient, = 0.463; = 0.010) and I-Pen ( = 0.449; = 0.013) systems. In addition, there was a strong correlation between the osmolarity scores obtained from the TearLab and I-Pen systems in smokers ( = 0.911; < 0.001).
Conclusion: The I-Pen scores in smokers were significantly higher than those obtained using TearLab. The TearLab scores showed small variations compared with those obtained using I-Pen. A strong correlation was found between the TearLab and I-Pen scores in smokers. The osmolarity TearLab and I-Pen scores were significantly higher in smokers compared with normal eye subjects.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9633209 | PMC |
| http://dx.doi.org/10.1155/2022/9970388 | DOI Listing |
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Article Synopsis
- The study investigates how smoking affects eye health by comparing osmolarity scores in smokers and non-smokers using two measurement systems, TearLab and I-Pen.
- Thirty male smokers and a matching control group of non-smokers participated, with results showing smokers had higher ocular surface disease index (OSDI) and osmolarity scores.
- The findings reveal a strong correlation between TearLab and I-Pen scores in smokers, with both systems indicating significantly poorer eye health compared to non-smokers.
The validity of point of care tear film osmometers in the diagnosis of dry eye.
Ophthalmic Physiol Opt
January 2022
School of Optometry and Vision Science, University of New South Wales, Sydney, New South Wales, Australia.
Purpose: To determine the repeatability of TearLab and I-PEN osmometers in vivo and their accuracy in vitro.
Design: Prospective, single-visit study.
Methods: The tear osmolarity of 28 participants was evaluated with TearLab and I-PEN on two occasions in random order, over a 2-h period.
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