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4-Amino-6-(piperidin-1-yl)pyrimidine-5-carbo-nitrile. | LitMetric

4-Amino-6-(piperidin-1-yl)pyrimidine-5-carbo-nitrile.

IUCrdata

Department of studies in Chemistry, Bangalore University, Jnana Bharathi Campus, Bangalore-560 056, Karnataka, India.

Published: March 2020

In the title compound, CHN, the piperidine ring adopts a chair conformation with the exocyclic N-C bond in an axial orientation, and the dihedral angle between the mean planes of piperidine and pyrimidine rings is 49.57 (11)°. A short intra-molecular C-H⋯N contact generates an (7) ring. In the crystal, N-H⋯N hydrogen bonds link the mol-ecules into (100) sheets and a weak aromatic π-π stacking inter-action is observed [centroid-centroid separation = 3.5559 (11) Å] between inversion-related pyrimidine rings.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462203PMC
http://dx.doi.org/10.1107/S2414314620003855DOI Listing

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