Bacteremia and polyarticular septic arthritis secondary to in a pregnant patient with HIV who injects drugs.

J Assoc Med Microbiol Infect Dis Can

Internal Medicine/Infectious Disease, College of Medicine, University of Saskatchewan, Saskatchewan, Saskatoon, Canada.

Published: June 2022

Case Presentation: We report a rare case of bacteremia and polyarticular septic arthritis in a 37-year-old pregnant woman with HIV who injects drugs. Two sets of blood cultures obtained 5 hours apart were positive for gram-negative bacilli, and purulent fluid was present intra-operatively from both her left knee and her right third MCP joints.

Diagnosis: Organism identification using ligation sequencing confirmed both her blood culture and synovial tissue isolates as . Her infection was initially treated with third-generation cephalosporins and later changed to moxifloxacin because of a drug reaction; although she defervesced clinically with improvement in her C-reactive protein levels, she died most likely as a result of a non-traumatic fat embolism after an elective cesarean delivery.

Discussion: In contrast to , other species are rarely associated with disease in human hosts. is classically associated with infectious bovine keratoconjunctivitis in cattle; interestingly, our patient denied significant animal exposure. To the authors' knowledge, this is the first case describing infection secondary to in an adult host.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9608112PMC
http://dx.doi.org/10.3138/jammi-2021-0027DOI Listing

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