AI Article Synopsis
- - Leishmaniasis, caused by Leishmania infantum, is a significant zoonotic disease primarily spread by sand flies, particularly affecting dogs and cats in endemic regions.
- - The disease can lead to systemic symptoms that vary in severity, impacting various organs such as the skin, lymph nodes, and kidneys, with dogs and cats showing generally similar clinical signs.
- - Treatment often involves long-term use of allopurinol, sometimes in combination with other medications, and there is a high likelihood of clinical relapse.
Article Abstract
Leishmaniasis caused by Leishmania infantum is an important zoonotic disease transmitted by sand flies with a high prevalence of infection in dogs and cats in regions whereby transmission occurs. Clinical disease is systemic with variable presenting signs and degrees of severity. It affects the skin, lymph nodes, eyes, bone marrow, kidneys, and other organs. The clinical findings in dogs and cats with L. infantum infection are generally similar. Subclinical infection of canines and felines in endemic areas is frequent. Long-term treatment of the disease with allopurinol, or combination of allopurinol with meglumine antimoniate or miltefosine, is needed, and clinical relapse is probable.
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| http://dx.doi.org/10.1016/j.cvsm.2022.06.012 | DOI Listing |
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