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http://dx.doi.org/10.1016/j.ebiom.2022.104332 | DOI Listing |
Sci Rep
December 2024
Department of Biology, University of Oxford, Oxford, OX1 3RB, UK.
Plant Cysteine Oxidases (PCOs) are oxygen-sensing enyzmes that catalyse oxidation of cysteinyl residues at the N-termini of target proteins, triggering their degradation via the N-degron pathway. PCO oxygen sensitivity means that in low oxygen conditions (hypoxia), their activity reduces and target proteins are stabilised. PCO substrates include Group VII Ethylene Response Factors (ERFVIIs) involved in adaptive responses to the acute hypoxia experienced upon plant submergence, as well as Little Zipper 2 (ZPR2) and Vernalisation 2 (VRN2) which are involved in developmental processes in hypoxic niches.
View Article and Find Full Text PDFDietary betaine supplementation has been reported to alleviate the adverse effects of high-carbohydrate diets on , while the regulatory mechanism remains largely unknown. In the present study, a 79-day feeding trial was conducted with 450 juvenile (average weight 6.75 ± 0.
View Article and Find Full Text PDFJ Anim Sci
January 2024
Graduate School of Agricultural Science, Tohoku University, Sendai 980-8572, Japan.
Taurine, biosynthesized from methionine or cysteine in the liver, plays a crucial regulatory role in bile acid conjugation, antioxidant effects, and glucose and cholesterol metabolism. This may influence the metabolic changes associated with fat accumulation in beef cattle. However, the physiological role of taurine in this species has not been fully elucidated.
View Article and Find Full Text PDFJ Anim Sci
January 2024
Department of Animal Sciences, Auburn University, Auburn, AL 36849, USA.
Weaning stress in pigs is associated with low feed intake and poor nutrient utilization. Cysteine is a sulfur amino acid with key roles in pig production, but how cysteine metabolism and requirements are affected by weaning stress should be better defined. The objective of this study was to determine the collective impact of weaning and feed restriction on tissue cysteine metabolism.
View Article and Find Full Text PDFFront Vet Sci
October 2024
Key Laboratory of Qinghai-Tibetan Plateau Animal Genetic Resource Reservation and Utilization, Ministry of Education, Chengdu, China.
Introduction: The CDO1 gene is an important gene in the taurine synthesis pathway and has been observed to have high expression in ovaries of female mammals. This study aims to explore the conservation of CDO1 gene in domestic yaks, as well as to examine the fundamental characteristics of CDO1 gene and its expression in female yaks.
Methods: Ovarian samples were collected from yaks in the follicular phase, luteal phase and gestation period in this experiment, and their total RNA and protein were extracted.
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