AI Article Synopsis
- The study investigates how the brain processes self-motion signals by using whole-brain neuroimaging to identify the egomotion network in a large group of participants.
- Key brain areas involved in this network were pinpointed, including the cingulate sulcus, cerebellum, and temporo-parietal cortex, suggesting a connection with multisensory integration and spatial awareness.
- Findings indicate that specific connections, particularly between the cingulate sulcus and cerebellum, play a crucial role in perceiving egomotion, enhancing our understanding of how different sensory inputs combine for movement perception.
Article Abstract
All volitional movement in a three-dimensional space requires multisensory integration, in particular of visual and vestibular signals. Where and how the human brain processes and integrates self-motion signals remains enigmatic. Here, we applied visual and vestibular self-motion stimulation using fast and precise whole-brain neuroimaging to delineate and characterize the entire cortical and subcortical egomotion network in a substantial cohort (n=131). Our results identify a core egomotion network consisting of areas in the cingulate sulcus (CSv, PcM/pCi), the cerebellum (uvula), and the temporo-parietal cortex including area VPS and an unnamed region in the supramarginal gyrus. Based on its cerebral connectivity pattern and anatomical localization, we propose that this region represents the human homologue of macaque area 7a. Whole-brain connectivity and gradient analyses imply an essential role of the connections between the cingulate sulcus and the cerebellar uvula in egomotion perception. This could be via feedback loops involved updating visuo-spatial and vestibular information. The unique functional connectivity patterns of PcM/pCi hint at central role in multisensory integration essential for the perception of self-referential spatial awareness. All cortical egomotion hubs showed modular functional connectivity with other visual, vestibular, somatosensory and higher order motor areas, underlining their mutual function in general sensorimotor integration.
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| http://dx.doi.org/10.1016/j.neuroimage.2022.119715 | DOI Listing |
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