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Factors affecting the quality of life of patients with medication-related osteonecrosis of the jaw during treatment: A quality-of-life survey and causal analysis.
J Craniomaxillofac Surg
June 2024
Department of Dentistry and Oral Surgery, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan. Electronic address:
This prospective cohort study aimed to investigate the impact of medication-related osteonecrosis of the jaw (MRONJ) on health-related quality of life (HRQOL) and oral health-related QOL (OHRQOL) and the association between the downstaging of MRONJ and OHRQOL. The HRQOL and OHRQOL of 44 patients with MRONJ were assessed using the SF-36v2 and the General Oral Health Assessment Index (GOHAI), respectively. Treatment was performed in accordance with the AAOMS position paper (2014).
View Article and Find Full Text PDFObjective: Patients taking antiresorptive medications in dental clinics are at risk of medication-related osteonecrosis of the jaw (MRONJ), which poses daily challenges for their clinicians. This paper aimed to summarize and revisit the three most recognized practice guidelines for the management and prevention of MRONJ, which were proposed by the American Association of Oral and Maxillofacial Surgeons (AAOMS), and presented by the Journal of Bone and Mineral Research (JBMR) and the Journal of Clinical Oncology (JCO). Results and case studies: The AAOMS position paper focused on risk stratification by different medications, management decision trees, risk factors, pathophysiology, and disease staging.
View Article and Find Full Text PDFPotential Relationship between Poor Oral Hygiene and MRONJ: An Observational Retrospective Study.
Int J Environ Res Public Health
April 2023
Department of Medical, Oral and Biotechnological Sciences, University Gabriele d'Annunzio, 66100 Chieti, Italy.
Medication-related osteonecrosis of the jaw (MRONJ) is a drug-related side effect linked but not limited to antiresorptive and antiangiogenic molecules. It recognizes several triggers in dental procedures, such as surgery, endodontic treatments, and root planing, but also prosthesis decubitus or with a spontaneous onset. Although there are many reports about the onset of this pathology, oral hygiene status is mainly described as a consequence of MRONJ.
View Article and Find Full Text PDFReply: AAOMS Position Paper on Medication-Related Osteonecrosis of the Jaws-2022 Update. Diagnostic Milestones, Doubts, and Perspectives on MRONJ.
J Oral Maxillofac Surg
November 2022
New York, New York.
Re: AAOMS Position Paper on Medication-Related Osteonecrosis of the Jaw-2022 Update.
J Oral Maxillofac Surg
November 2022
Alessandria, Italy.
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