A phytochemical investigation on 90% methanol extract from the leaves of led to the isolation of three new triterpenoids, jugsigiloids A-C (-). Structural elucidation of all the compounds were performed by spectral methods such as 1 D and 2 D (H-H COSY, HMQC, and HMBC) NMR spectroscopy, in addition to high resolution mass spectrometry. The isolated components were evaluated for anti-inflammatory activities against COX-1 and COX-2 and radical scavenging potential using DPPH test. As a result, triterpenoid exhibited selective inhibition on COX-2 (93.2%) at the concentration of 100 μM and significant DPPH scavenging activity (IC = 41.6 μM) comparable with positive control Trolox (IC = 42.8 μM).
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http://dx.doi.org/10.1080/10286020.2022.2137023 | DOI Listing |
Nanomaterials (Basel)
March 2025
Department of Biotechnology and Bioinformatics, Yogi Vemana University, Kadapa 516005, India.
The use of metal nanoparticles is gaining popularity owing to their low cost and high efficacy. We focused on green synthesis of silver nanoparticles (AgNPs) using (Tc) leaf extracts. The structural characteristics of Tc nanoparticles (TcAgNPs) were determined using several advanced techniques.
View Article and Find Full Text PDFCell Prolif
March 2025
Department of Neurosurgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.
Glioblastoma multiforme (GBM) is the deadliest brain tumour with an extremely poor prognosis. Tryptophan catabolism could enhance an array of protumour-genic signals and promoted tumour progression in GBM. However, the mechanisms of oncogenic signalling under tryptophan catabolism and potential therapy targeting this pathway have not been completely understood.
View Article and Find Full Text PDFJ Cosmet Dermatol
March 2025
R&D Innovation Center, Shandong Freda Biotech Co., Ltd., Jinan, Shandong, P. R. China.
Objective: Oxidative stress activates the reactive oxygen species (ROS) and excessive ROS can damage skin cells, initiating oxidative stress responses that contribute to inflammation, aging, and other skin issues. As a resident skin bacterium, Cutibacterium acnes (C. acnes) plays an important role in maintaining skin homeostasis and provides antioxidant benefits.
View Article and Find Full Text PDFFront Plant Sci
February 2025
School of Agricultural Technology, King Mongkut's Institute of Technology Ladkrabang, Bangkok, Thailand.
The jasmine ( (L.) Aiton) flower has delicate petals, resulting in rapid browning after harvest. The aim of this study was to search for an innovative postharvest treatment for delaying browning of jasmine petals using plant essential oils.
View Article and Find Full Text PDFPhytochem Anal
March 2025
Department of Natural Medicine, School of Pharmacy, Fudan University, Shanghai, China.
Introduction: Myricariae Ramulus (MR) is a traditional anti-inflammatory Tibetan medicine derived from the branches and leafy twigs of various Myricaria plants, such as Myricaria wardii Marquand.
Objective: This study performed spectrum-effect analyses on 15 batches of MR, sourced from various origins and medicinal parts, to identify quality markers associated with its anti-inflammatory effects.
Materials And Methods: The anti-inflammatory effects of different extracts and fractions from M.
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