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Influence of Menstrual Cycle and Oral Contraceptive Phases on Bone (re)modelling Markers in Response to Interval Running.
Calcif Tissue Int
October 2024
LFE Research Group, Department of Health and Human Performance. Faculty of Physical Activity and Sport Science, Universidad Politécnica de Madrid, Calle de Martín Fierro, 7, 28040, Madrid, Spain.
Article Synopsis
- - The study investigated how sex hormone levels fluctuate throughout the menstrual cycle and the use of oral contraceptives (OC) affect bone metabolism markers, specifically P1NP and β-CTX-1, during exercise.
- - Eight women with regular menstrual cycles and eight OC users performed an 8x3 minute treadmill running test, with hormonal levels measured before and after exercise across different cycle phases.
- - Results showed significant variations in hormone levels: estrogen was lowest in the early-follicular phase and highest in the late-follicular phase; progesterone peaked in the mid-luteal phase, while post-exercise P1NP levels were notably higher in regular cycle phases compared to the active pill phase.
Leveraging code-free deep learning for pill recognition in clinical settings: A multicenter, real-world study of performance across multiple platforms.
Artif Intell Med
April 2024
Department of Pharmaceutics and Central Clinical Pharmacy, Faculty of Pharmacy, University of Pécs, Pécs, Hungary.
Background: Preventable patient harm, particularly medication errors, represent significant challenges in healthcare settings. Dispensing the wrong medication is often associated with mix-up of lookalike and soundalike drugs in high workload environments. Replacing manual dispensing with automated unit dose and medication dispensing systems to reduce medication errors is not always feasible in clinical facilities experiencing high patient turn-around or frequent dose changes.
View Article and Find Full Text PDFA step change model analysis of the establishment of pill testing in one Australian jurisdiction.
Harm Reduct J
November 2023
Harm Reduction Australia, 17 Glenugie St, Maroubra, NSW, 2035, Australia.
This paper applies the theory of change model (Kotter in Harv Bus Rev 2:59-67, 1995; Moore et al. in Viet Nam J Public Health 1(1):66-75, 2013) to describe the pathway that lead to Australia's first pill testing/drug checking services in Canberra, in the Australian Capital Territory. The paper takes each step of the model and illustrates the key activities that largely occurred over an approximately 24 month period resulting in the service being operational on 29 April 2018.
View Article and Find Full Text PDFUnannounced phone-based pill counts for monitoring antiretroviral medication adherence in South Africa.
HIV Res Clin Pract
December 2023
Health Systems Research Unit, South African Medical Research Council, Cape Town, South Africa.
Background: Unannounced phone-based pill counts (UPC) are an objective measure of medication adherence that may be used in resource limited settings. The current study reports the feasibility and validity of UPC for monitoring antiretroviral therapy (ART) adherence among people living with HIV in South Africa. People living with HIV ( = 434) in an economically impoverished township and receiving ART for at least 3-months completed: two UPC in a one-month period; measures of clinic and medication experiences; and provided blood samples for HIV viral load and CD4 testing.
View Article and Find Full Text PDFCORE™ wearable sensor: Comparison against gastrointestinal temperature during cold water ingestion and a 5 km running time-trial.
J Therm Biol
July 2023
Faculty of Physical Activity Sciences, University of Sherbrooke, Sherbrooke, Québec, Canada; Research Centre on Aging, University of Sherbrooke, Sherbrooke, Québec, Canada. Electronic address:
Five km running time-trials (TT) are associated with rapid and significant increases in core body temperature (T). For such races, real-time feedback from pre-exercise and exercise T may be helpful in the design of an optimal pacing strategy aimed at limiting the possibility of developing heat-related illnesses. This study compared measurements of T obtained with a wearable device, the CORE™, to those of a gastrointestinal pill (GI pill), during cold water ingestion and a 5 km running TT.
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