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Arthroscopic Reconstruction of the Acetabular Labrum Using an Autograft Hip Capsule.
JBJS Essent Surg Tech
December 2024
Sports Medicine Center, Department of Orthopaedics, Massachusetts General Hospital, Mass General Brigham, Boston, Massachusetts.
Background: Whereas uncomplicated labral tears with preserved fibers can be effectively treated with use of labral repair techniques, complex tears and hypoplastic labra require labral reconstruction. Standard reconstruction techniques feature grafted tissue that is added to existing, deficient tissue or that is utilized to replace a hypoplastic labrum entirely. However, such approaches utilizing allografts or remote autografts are limited because they often necessitate extensive debridement of the existing labrum to prepare a site for graft implantation, an approach that can damage and devascularize the chondrolabral junction.
View Article and Find Full Text PDFKnot data analysis using multiscale Gauss link integral.
Proc Natl Acad Sci U S A
October 2024
Department of Mathematics, Michigan State University, East Lansing, MI 48824.
Article Synopsis
- - Topological data analysis has gained traction in data science, but traditional knot theory struggles with practical use due to localization and quantization issues.
- - The introduction of knot data analysis (KDA) integrates curve segmentation and multiscale analysis into the Gauss link integral (mGLI), enabling a better understanding of global and local topological structures in data.
- - By combining mGLI with machine learning techniques, KDA outperforms existing methods on 13 complex biological datasets, paving the way for a new research area called "knot deep learning."
Efficient control of root-knot nematodes by expressing Bt nematicidal proteins in root leucoplasts.
Mol Plant
October 2024
State Key Laboratory of Biocatalysis and Enzyme Engineering, Hubei Hongshan Laboratory, School of Life Sciences, Hubei University, Wuhan 430062, China; Shenzhen Branch, Guangdong Laboratory of Lingnan Modern Agriculture, Key Laboratory of Synthetic Biology, Ministry of Agriculture and Rural Affairs, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen 518000, China. Electronic address:
Root-knot nematodes (RKNs) are plant pests that infect the roots of host plants. Bacillus thuringiensis (Bt) nematicidal proteins exhibited toxicity to nematodes. However, the application of nematicidal proteins for plant protection is hampered by the lack of effective delivery systems in transgenic plants.
View Article and Find Full Text PDFUnraveling the Roles of Neuropeptides in the Chemosensation of the Root-Knot Nematode .
Int J Mol Sci
June 2024
Department of Botany and Plant Pathology, Purdue University, West Lafayette, IN 47907, USA.
The identification of novel drug targets in plant-parasitic nematodes (PPNs) is imperative due to the loss of traditional nematicides and a lack of replacements. Chemosensation, which is pivotal for PPNs in locating host roots, has become a focus in nematode behavioral research. However, its underlying molecular basis is still indistinct in such a diverse group of PPNs.
View Article and Find Full Text PDFXinyang flavivirus, from ticks in Henan Province, China, defines a basal, likely tick-only clade.
J Gen Virol
May 2024
School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, QLD, Australia.
Tick-borne orthoflaviviruses (TBFs) are classified into three conventional groups based on genetics and ecology: mammalian, seabird and probable-TBF group. Recently, a fourth basal group has been identified in ticks from Africa: Mpulungu flavivirus (MPFV) in Zambia and Ngoye virus (NGOV) in Senegal. Despite attempts, isolating these viruses in vertebrate and invertebrate cell lines or intracerebral injection of newborn mice with virus-containing homogenates has remained unsuccessful.
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