Background: Patients diagnosed with cancer and who undergo cancer treatment are at potential risk of bone marrow suppression leading to prolonged hospitalization, delay in treatment, and chemotherapy dose reductions, which ultimately results in significant morbidity and mortality. This sequential exploratory study using a mixed-method approach was aimed to develop and validate a neutropenic nursing care (NNC) bundle for neutropenic patients admitted in a tertiary care hospital, Uttarakhand.
Material And Methods: This sequential exploratory study design with an instrument developmental model was used to develop the NNC bundle. It consisted of two phases: Qualitative phase and quantitative phase. In the qualitative phase, focused group discussion with eight oncology nurses was performed to derive themes related to neutropenic nursing care using conventional content analysis. An extensive literature review was also performed on these themes to explore the current pieces of evidence for item pool generation. In the quantitative phase, a preliminary draft bundle was developed, and two Delphi rounds (I and II) were carried out among the five experts for the content validation of the NNC bundle and a final bundle was developed.
Results: Major domains identified for the bundle were hand hygiene, care of central and peripheral lines, routine oral care, antiseptic bath, peri-anal care, diet, and environmental hygiene. The content validity index (CVI) of the bundle was found to be >80% for all the items with I-CVI >0.8 and S-CVI = 0.99 after conducting two rounds of Delphi.
Conclusion: The present study has provided a set of valid written neutropenic nursing interventions to prevent complications in neutropenic patients. The NNC bundle should be subjected to other levels of evaluation that measure the bundle's practicability and suitability for the intended field.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9621356 | PMC |
| http://dx.doi.org/10.4103/jehp.jehp_241_22 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
A liberalized diet does not improve caloric intake during neutropenia in patients undergoing hematopoietic stem cell transplants: A prospective randomized controlled trial.
Nutr Clin Pract
December 2024
Department of Food Science and Human Nutrition, University of Florida/IFAS, Gainesville, Florida, USA.
Background: The neutropenic diet has been a long-standing approach to preventing infection in patients with hematopoietic stem cell transplants (HSCTs), although data on its efficacy are inconclusive and its restrictive nature might contribute to harm by reducing dietary intake in this patient population who typically experiences poor oral intake. The aim was to determine if a liberalized diet (LD), in comparison with a neutropenic hospital diet (ND), would improve energy intake and lessen weight loss during neutropenia in patients with HSCTs.
Methods: A randomized controlled trial was conducted in a single-center HSCT/hematologic malignancy unit.
At-Home Care Versus Total Hospital Care Model for Autologous Stem Cell Transplantation in Adult Lymphoma Patients: A Pilot Case-Control Study.
Cancer Nurs
September 2024
Author Affiliations: Hematology and Hemotherapy Department, Hospital Clínico Universitario de Valencia (Ms Hernández-Aliaga, Dr Carretero-Márquez, and Mr Santacatalina-Roig); Nursing Department, Nursing and Podiatry Faculty, University of Valencia (Ms Hernández-Aliaga and Dr Navarro-Martínez); and Haematopoietic Transplantation Research Group (INCLIVA) (Ms Hernández-Aliaga and Mr Peña) and Care Research Group (INCLIVA) (Dr Navarro-Martínez), Hospital Clínico Universitario de Valencia, Spain.
Background: Lymphoma is the second most prevalent cancer treated with autologous stem cell transplantation (ASCT). Additional resources are required to enhance the provision of care for these patients.
Objective: To explore the complications and economic costs of home versus hospital care models for ASCT in patients diagnosed with lymphoma and to describe the experience of home care patients.
Growth Factor in the Setting of CAR T-Cell Therapy: To Use or Not to Use.
J Adv Pract Oncol
May 2024
From The University of Texas MD Anderson Cancer Center, Houston, Texas.
Patients undergoing chimeric antigen receptor (CAR) T-cell therapy may experience side effects including cytokine release syndrome (CRS), immune effector cell-associated neurotoxicity syndrome (ICANS), neutropenia, and infection. Growth factor has historically been used to treat neutropenia; however, its role in CAR T-cell therapy is not well explained. Existing data on the safety and efficacy of growth factor are conflicting.
View Article and Find Full Text PDFPredicting Neutropenic Sepsis in Patients with Hematologic Malignancy: A Retrospective Case-Control Study.
Clin Nurs Res
November 2024
College of Nursing, The Catholic University of Korea, Seoul, South Korea.
Article Synopsis
- - Neutropenic sepsis (NS) is a significant cause of death in patients with blood cancers, and identifying predictive factors is essential for timely treatment.
- - The study analyzed data from 163 patients, identifying average body temperature and procalcitonin levels as key predictors of NS, with specific cutoff points of 37.9°C and 0.55 ng/mL, respectively.
- - Results showed that the risk of NS increased significantly with rising body temperature and procalcitonin, highlighting the importance of monitoring these factors in clinical settings.
Correction: Ishikawa et al. Systematic Review of Beta-Lactam vs. Beta-Lactam plus Aminoglycoside Combination Therapy in Neutropenic Cancer Patients. 2024, , 1934.
Cancers (Basel)
June 2024
Department of Infectious Diseases, St. Luke's International Hospital, Tokyo 104-8560, Japan.
There was an error in the original publication [...
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!