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ARCH: Large-scale knowledge graph via aggregated narrative codified health records analysis.
J Biomed Inform
January 2025
Harvard T.H. Chan School of Public Health, 677 Huntington Ave, Boston, 02115, MA, USA; VA Boston Healthcare System, 150 S Huntington Ave, Boston, 02130, MA, USA. Electronic address:
Objective: Electronic health record (EHR) systems contain a wealth of clinical data stored as both codified data and free-text narrative notes (NLP). The complexity of EHR presents challenges in feature representation, information extraction, and uncertainty quantification. To address these challenges, we proposed an efficient Aggregated naRrative Codified Health (ARCH) records analysis to generate a large-scale knowledge graph (KG) for a comprehensive set of EHR codified and narrative features.
View Article and Find Full Text PDFHost RNA-Binding Proteins as Regulators of HIV-1 Replication.
Viruses
December 2024
Laboratory of Molecular and Cellular Virology, Institute of Biomedical Sciences, Faculty of Medicine, Universidad de Chile, Santiago 8380453, Chile.
RNA-binding proteins (RBPs) are cellular factors involved in every step of RNA metabolism. During HIV-1 infection, these proteins are key players in the fine-tuning of viral and host cellular and molecular pathways, including (but not limited to) viral entry, transcription, splicing, RNA modification, translation, decay, assembly, and packaging, as well as the modulation of the antiviral response. Targeted studies have been of paramount importance in identifying and understanding the role of RNA-binding proteins that bind to HIV-1 RNAs.
View Article and Find Full Text PDFThe Physicochemical and Rheological Properties of Green Banana Flour-Wheat Flour Bread Substitutions.
Plants (Basel)
January 2025
Faculty of Science, School of Agriculture, Food and Ecosystem Sciences, The University of Melbourne, Parkville, VIC 3010, Australia.
Functional foods are currently receiving increasing popularity in diet modification. Green bananas contain far more dietary fiber (DF) and resistant starch (RS) than mature bananas. The potential for integrating these vital components into food, such as bread, has expanded.
View Article and Find Full Text PDFElephant Sound Classification Using Deep Learning Optimization.
Sensors (Basel)
January 2025
School of Computer Science and Informatics, Cardiff University, Cardiff CF24 3AA, UK.
Elephant sound identification is crucial in wildlife conservation and ecological research. The identification of elephant vocalizations provides insights into the behavior, social dynamics, and emotional expressions, leading to elephant conservation. This study addresses elephant sound classification utilizing raw audio processing.
View Article and Find Full Text PDFCarbon Nanosphere-Based TiO Double Inverse Opals.
Molecules
January 2025
Institute of Physical Metallurgy, Metal Forming and Nanotechnology, University of Miskolc, H-3515 Miskolc, Hungary.
Inverse opals (IOs) are intensively researched in the field of photocatalysis, since their optical properties can be fine-tuned by the initial nanosphere size and material. Another possible route for photonic crystal programming is to stack IOs with different pore sizes. Accordingly, single and double IOs were synthesized using vertical deposition and atomic layer deposition.
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