This study performed trace detection using surface-enhanced Raman scattering (SERS) on Au hexagonal cone arrays (Au-HCAs). Uniform porous anodized aluminum oxide (AAO) templates were used, and an Ag film with a cone cavity was prepared using a thermal deposition technique. Next, a series of homogeneous Au-HCAs were prepared controllably via electrodeposition growth technology. The prepared Au-HCAs were used as SERS substrates, and according to the experimental results, the optimal electrodeposition time is 600 s. At this time, Au-HCAs had the highest SERS activity. The detection limit of R6G was 10 M, exhibiting high reproducibility and high uniformity at 10 M, indicating that Au-HCAs had good stability. Moreover, a good linear correlation between the Raman intensity and the molecular concentration endowed Au-HCAs with good quantitative analysis ability. Therefore, the Au-HCAs exhibited great potential for qualitative and quantitative detection.
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http://dx.doi.org/10.1016/j.saa.2022.121969 | DOI Listing |
Cell
January 2025
Department of Molecular Sociology, Max Planck Institute of Biophysics, Max-von-Laue-Straße 3, 60438 Frankfurt am Main, Germany; Institute of Biochemistry, Goethe University Frankfurt, 60438 Frankfurt am Main, Germany. Electronic address:
Upon infection, human immunodeficiency virus type 1 (HIV-1) releases its cone-shaped capsid into the cytoplasm of infected T cells and macrophages. The capsid enters the nuclear pore complex (NPC), driven by interactions with numerous phenylalanine-glycine (FG)-repeat nucleoporins (FG-Nups). Whether NPCs structurally adapt to capsid passage and whether capsids are modified during passage remains unknown, however.
View Article and Find Full Text PDFJ Appl Clin Med Phys
November 2024
Department of Computer Science, Mathematics, Physics and Statistics, The University of British Columbia Okanagan, Kelowna, British Columbia, Canada.
Purpose: To evaluate the feasibility of an open-source, semi-automated, and reproducible vertex placement tool to improve the efficiency of lattice radiotherapy (LRT) planning. We used polymer gel dosimetry with a Cone Beam CT (CBCT) readout to commission this LRT technique.
Material And Methods: We generated a volumetric modulated arc therapy (VMAT)-based LRT plan on a 2 L NIPAM polymer gel dosimeter using our Eclipse Acuros version 15.
Viruses
June 2024
Department of Molecular Physiology and Biological Physics, University of Virginia, Charlottesville, VA 22903, USA.
In the fullerene cone HIV-1 capsid, the central channels of the hexameric and pentameric capsomers each contain a ring of arginine (Arg18) residues that perform essential roles in capsid assembly and function. In both the hexamer and pentamer, the Arg18 rings coordinate inositol hexakisphosphate, an assembly and stability factor for the capsid. Previously, it was shown that amino-acid substitutions of Arg18 can promote pentamer incorporation into capsid-like particles (CLPs) that spontaneously assemble in vitro under high-salt conditions.
View Article and Find Full Text PDFSensors (Basel)
June 2024
School of Information and Communications Engineering, Xi'an Jiaotong University, Xi'an 710049, China.
Array pattern synthesis with low sidelobe levels is widely used in practice. An effective way to incorporate sensor patterns in the design procedure is to use numerical optimization methods. However, the dimension of the optimization variables is very high for large-scale arrays, leading to high computational complexity.
View Article and Find Full Text PDFAdv Sci (Weinh)
August 2024
College of Integrated Circuits, Hangzhou Global Scientific and Technological Innovation Centre, Zhejiang University, 38 Zheda Road, Hangzhou, 310027, China.
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