Race and Ancestry in Immune Response to Breast Cancer.

Cancer Discov

Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.

Published: November 2022

Martini and colleagues performed genetic ancestry estimation on a unique international triple-negative breast cancer (TNBC) study enriched for participants with African ancestry. They identified gene signatures indicative of ancestry in race-associated TNBC and found ancestry-associated immunologic differences that may contribute to racial disparities in breast cancer. See related article by Martini et al., p. 2530 (5).

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10071672PMC
http://dx.doi.org/10.1158/2159-8290.CD-22-0852DOI Listing

Publication Analysis

Top Keywords

breast cancer
12
race ancestry
4
ancestry immune
4
immune response
4
response breast
4
cancer martini
4
martini colleagues
4
colleagues performed
4
performed genetic
4
genetic ancestry
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!