Molecular characterization of canine and feline kobuvirus infections in Iran.

Vet Res Forum

Department of Microbiology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.

Published: September 2022

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Article Abstract

Kobuviruses are viral pathogens with broad host range presented in human gastroenteritis cases; but, the pathogenesis of these viruses in companion animals is not well described. In the present study, the presence of canine (CaKVs) and feline kobuviruses (FeKVs) was detected in the 100 fecal samples of diarrhoeic and healthy companion dogs and cats by polymerase chain reaction in Tehran, Iran. The prevalence of infection was estimated as 8.00% and 4.00% in dogs and cats, respectively. All positive samples were belonged to non-diarrhoeic animals except for a feline sample being co-infected with panleukopenia. Sequence analysis showed multiple point mutations in canine and feline Iranian strains and new feline strain was detected in the present study. This is the first detection of CaKVs and FeKVs in Iran; but, the exact role of these enteric viral pathogens and their zoonotic risks are better to be clarified in all endemic regions.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9548235PMC
http://dx.doi.org/10.30466/vrf.2020.128667.2975DOI Listing

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