Artifacts in the Electrocardiogram (ECG) degrade the quality of the recorded signal and are not conducive to heart rate variability (HRV) analysis. The two types of noise most often found in ECG recordings are technical and physiological artifacts. Current preprocessing methods primarily attend to ectopic beats but do not consider technical issues that affect the ECG. A secondary aim of this study was to investigate the effect of increasing increments of artifacts on 24 of the most used HRV measures. A two-step preprocessing approach for denoising HRV is introduced which targets each type of noise separately. First, the technical artifacts in the ECG are eliminated by applying complete ensemble empirical mode decomposition with adaptive noise. The second step removes physiological artifacts from the HRV signal using a combination filter of single dependent rank order mean and an adaptive filtering algorithm. The performance of the two-step pre-processing tool showed a high correlation coefficient of 0.846 and RMSE value of 7.69 × 10 for 6% of added ectopic beats and 6 dB Gaussian noise. All HRV measures studied except HF peak and LF peak are significantly affected by both types of noise. Frequency measures of Total power, HF power, and LF power and fragmentation measures; PAS, PIP, and PSS are the most sensitive to both types of noise.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9626590PMC
http://dx.doi.org/10.1038/s41598-022-21776-2DOI Listing

Publication Analysis

Top Keywords

types noise
12
two-step pre-processing
8
pre-processing tool
8
heart rate
8
rate variability
8
physiological artifacts
8
ectopic beats
8
artifacts hrv
8
hrv measures
8
power power
8

Similar Publications

Expression quantitative trait loci (eQTLs) provide a key bridge between noncoding DNA sequence variants and organismal traits. The effects of eQTLs can differ among tissues, cell types, and cellular states, but these differences are obscured by gene expression measurements in bulk populations. We developed a one-pot approach to map eQTLs in by single-cell RNA sequencing (scRNA-seq) and applied it to over 100,000 single cells from three crosses.

View Article and Find Full Text PDF

Audiometric Profile of Presbyacusis in North India: Georgean Experience of 7000 Cases.

Indian J Otolaryngol Head Neck Surg

February 2025

Department of Otorhinolaryngology and Head & Neck Surgery, King George Medical University, Lucknow, India.

Background: Presbyacusis is common in early 50s, while genetic/ environmental influences that differentially affect presbyacusis seem relevant in racial and regional perspective.

Aim: To describe audiometric profile of presbyacusis in North India and its relevance with age/ gender/ associated comorbidities.

Methods: Audiometric profile of about 7000 patients (> 50y) with SNHL were analysed in terms of curve-profile ('Flat', 'High-Frequency Gently Sloping', 'High-Frequency Steeply Sloping'), 'Mixed category', 'Interaural Asymmetry' and 'Notched Hearing Loss' along with their association with age, gender and co-morbidity status.

View Article and Find Full Text PDF

Enhancing single-cell classification accuracy using image conversion and deep learning.

Yi Chuan

March 2025

College of Animal Science and Technology, Yangtze University, Jingzhou 434025, China.

Single-cell transcriptome sequencing (scRNA-seq) is widely used in the fields of animal and plant developmental biology and important trait analysis by obtaining single-cell transcript abundance data in high throughput, which can deeply reveal cell types, subtype composition, specific gene markers and functional differences. However, scRNA-seq data are often accompanied by problems such as high noise, high dimensionality and batch effect, resulting in a large number of low-expressed genes and variants, which seriously affect the accuracy and reliability of data analysis. This not only increases the complexity of data processing, but also limits the effectiveness of feature selection and downstream analysis.

View Article and Find Full Text PDF

Objectives: A problem currently faced in the assessment of human exposure to the external environment concerns sources of noise with significant energy found in the range of infrasound and low sound frequencies. This paper presents an analysis of selected low-frequency noise (LFN) sources in order to demonstrate the problem of the potential exposure of humans residing in their vicinity. There are numerous machines in industry that emit LFN, including infrasound, such as ventilation systems, industrial fans, air and exhaust transfer systems, means of transport and other objects that generate secondary noise, such as acoustic screens.

View Article and Find Full Text PDF

Augmenting the human interactome for disease prediction through gene networks inferred from human cell atlas.

Anim Cells Syst (Seoul)

March 2025

Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul, Republic of Korea.

Gene co-expression network inference from bulk tissue samples often misses cell-type-specific interactions, which can be detected through single-cell gene expression data. However, the noise and sparsity of single-cell data challenge the inference of these networks. We developed scNET, a framework for integrative cell-type-specific co-expression network inference from single-cell transcriptome data, demonstrating its utility in augmenting the human interactome for more accurate disease gene prediction.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!