The incidence of melanoma in Central Hesse, the catchment area of the Dermatological Clinic of the University of Giessen, was 11.1 per 100,000 inhabitants in 1984. The incidences in the different districts are relatively equa, varying only between 9.7 and 12.4 in 5 of 6 districts. In Central Hesse, too, the frequency of melanoma has steadily increased since 1970, the rates for 1984 being fivefold in both men and women. Apart from the real increase, this is probably due to an intensive public and professional melanoma education project and higher public awareness.
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J Neurointerv Surg
January 2025
Semmes-Murphey Neurologic and Spine Institute, Memphis, Tennessee, USA.
Background: Studies have described a first pass effect (FPE) where patients with successful recanalization after one pass experience better outcomes. Few studies have evaluated this in patients with large core infarctions.
Objective: To determine whether patients with large core infarcts undergoing mechanical thrombectomy in which first pass reperfusion is achieved experience improved outcomes compared with those who undergo more than one pass.
Psychiatr Prax
January 2025
Klinik für Gerontopsychiatrie, Psychosomatik und Psychotherapie, Pfalzklinikum für Psychiatrie und Neurologie AdöR, Klingenmünster.
As part of the largest model project in Germany in accordance with § 64b SGB V at the Pfalzklinikum, a clearing concept was developed in the Clinic for Geriatric Psychiatry to ensure rapid and adequate diagnosis and effective referral to the further treatment setting. Retrospective data of all clearing cases from the first year are presented. In addition to demographic data and treatment diagnoses, the distribution of patients across settings providing further treatment is presented.
View Article and Find Full Text PDFStem Cell Res
February 2025
Institute of Physiology I, Medical Faculty, University of Bonn, Germany. Electronic address:
BAG3 plays a key role in proteostasis as a central component of the chaperone-assisted selective autophagy (CASA) complex. A point mutation (p.P209L; c.
View Article and Find Full Text PDFStem Cell Res
February 2025
Institute of Physiology I, Medical Faculty, University of Bonn, Germany. Electronic address:
BAG3 is a central component of the chaperone-assisted selective autophagy complex and thus important for proteostasis. This function is affected by a point mutation (p.P209L; c.
View Article and Find Full Text PDFTrials
November 2024
Institute of Clinical Epidemiology and Biometry, Julius-Maximilians-Universität Würzburg, Würzburg, Germany.
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