A systematic review of the literature was conducted to identify course-based undergraduate research experiences (CUREs) in science, technology, engineering, and math (STEM) courses within the years 2000 through 2020. The goals of this review were to 1) create a resource of STEM CUREs identified by their discipline, subdiscipline, and level; 2) determine the activities included in each CURE, particularly the primary components listed in the CURE definition as well as specific science practices we identified as key to scientific reasoning; and 3) identify the next steps needed in CURE creation and implementation. Our review found 242 CURE curricula described in 220 total articles, with most described in biology, although STEM disciplines, including chemistry and biochemistry, have begun to publish CURE curricula as well. We also found that most CUREs include the primary components. However, when we look at the specific science practices essential to scientific reasoning, we found that these are less common in many CUREs and are implemented differently. We encourage CURE authors to consider including these science practices and potentially measuring their impact on student outcomes. The present work provides a summary of the current published CUREs, their disciplines, course levels, primary components, and specific science practices.
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http://dx.doi.org/10.1187/cbe.22-04-0069 | DOI Listing |
JAMA Netw Open
January 2025
Division of Endocrinology and Metabolism, Department of Medicine, University of Calgary, Calgary, Alberta, Canada.
Importance: Using albumin-adjusted calcium is commonly recommended for for measuring calcium, but with little empirical evidence to support the practice.
Objective: To assess the correlation between total calcium measurements (with or without adjustment) vs the ionized calcium level as a reference standard.
Design, Setting, And Participants: This was a population-based cross-sectional study in the province of Alberta, Canada, including adults tested for serum total calcium and ionized calcium simultaneously between January 1, 2013, and October 31, 2019.
JAMA Pediatr
January 2025
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Importance: Spontaneous reports have indicated that montelukast increases the risk of neuropsychiatric adverse events, and the US Food and Drug Administration added a boxed warning about these risks in 2020. However, the potential mechanism is not well understood, and the observational evidence is scarce, particularly in children.
Objective: To assess the potential association between the use of montelukast and the risk of neuropsychiatric adverse events in children and adolescents.
Langmuir
January 2025
Department of Engineering Science, University of Oxford, Oxford OX1 3PJ, United Kingdom.
Mass transfer governs the overall catalytic performance of heterogeneous catalysts considerably; however, this fundamental research has often been ignored. Here, macroporous SiO-supported Pt nanoparticle (Pt/SiO-M) and mesoporous SiO-supported Pt nanoparticle (Pt/SiO-m) catalysts were specifically fabricated by a facile thermal reduction step to engineer the resultant Pt nanoparticles showing similar physiochemical properties while possessing completely different porous microstructures exclusively originating from SiO supports. On this basis, a platform to explore the crucial mass transfer difference affecting catalytic activity is then established by systematically practicing industry-important benzene oxidation measurements.
View Article and Find Full Text PDFStem Cells Dev
January 2025
Department of Clinical Pharmacy and Pharmacy Practices, Faculty of Pharmacy, University Malaya, Kuala Lumpur, Malaysia.
Hypertension, commonly known as high blood pressure, is a significant health issue that increases the risk of cardiovascular diseases, stroke, and renal failure. This condition broadly encompasses both primary and secondary forms. Despite extensive research, the underlying mechanisms of systemic arterial hypertension-particularly primary hypertension, which has no identifiable cause and is affected by genetic and lifestyle agents-remain complex and not fully understood.
View Article and Find Full Text PDFArch Pathol Lab Med
January 2025
the Department of Pathology, The Ohio State University, Columbus (Parwani).
Context.—: Generative artificial intelligence (AI) has emerged as a transformative force in various fields, including anatomic pathology, where it offers the potential to significantly enhance diagnostic accuracy, workflow efficiency, and research capabilities.
Objective.
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