Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1164/rccm.202107-1692IM | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Proteomic, metabolomic and lipidomic profiles in community acquired pneumonia for differentiating viral and bacterial infections.
Sci Rep
January 2025
Fraunhofer Institute for Translational Medicine and Pharmacology (ITMP), Theodor-Stern-Kai 7, 60596, Frankfurt am Main, Germany.
Community-acquired pneumonia (CAP) has a significant impact on public health, especially in light of the recent SARS-CoV-2 pandemic. To enhance disease characterization and improve understanding of the underlying mechanisms, a comprehensive analysis of the plasma lipidome, metabolome and proteome was conducted in patients with viral and bacterial CAP infections, including those induced by SARS-CoV-2. Lipidomic, metabolomic and proteomic profiling were conducted on plasma samples of 69 patients suffering either from viral or bacterial CAP.
View Article and Find Full Text PDFNew quinazolone-sulfonate conjugates with an acetohydrazide linker as potential antimicrobial agents: design, synthesis and molecular docking simulations.
RSC Adv
January 2025
Department of Therapeutic Chemistry, Pharmaceutical and Drug Industries Research Institute, National Research Centre Dokki Giza 12622 Egypt
A novel molecular design based on a quinazolinone scaffold was developed the attachment of aryl alkanesulfonates to the quinazolinone core through a thioacetohydrazide azomethine linker, leading to a new series of quinazolinone-alkanesulfonates 5a-r. The antimicrobial properties of the newly synthesized quinazolinone derivatives 5a-r were investigated to examine their bactericidal and fungicidal activities against bacterial pathogens like , (Gram-positive), , , (Gram-negative), in addition to (unicellular fungal). The tested compounds demonstrated reasonable bactericidal activities compared to standard drugs.
View Article and Find Full Text PDFExogenous Lipoid Pneumonia.
N Engl J Med
January 2025
Kanagawa Cardiovascular and Respiratory Center, Yokohama, Japan
Morbidity and mortality associated with ESBL Klebsiella pneumoniae infection in different administration routes in albino rats.
Cell Mol Biol (Noisy-le-grand)
January 2025
Department of Medical Microbiology, Faculty of Science and Health, Koya University, Koya KOY45, Kurdistan Region-F.R., Iraq.
Klebsiella pneumoniae is a non-motile, encapsulated, environmental gram-negative bacterium. Once the bacteria have infiltrated the body, they can display substantial degrees of resistance to drugs and virulence. Extended Spectrum Beta-Lactamases (ESBLs) are most typically seen in K.
View Article and Find Full Text PDFExogenous Lipoid Pneumonia after Long-Term Nasal Petroleum Jelly Application.
Radiol Cardiothorac Imaging
February 2025
From the Department of Diagnostic and Interventional Radiology (D.B., M.H.P.) and Department of Pathology and Cytology (S.S.J.), University Hospital Center Zagreb, Kišpatićeva 12, 10 000 Zagreb, Croatia; Clinic for Lung Diseases Jordanovac, University Hospital Center Zagreb, Zagreb, Croatia (M.K.); and University of Zagreb School of Medicine, Zagreb, Croatia (M.K., S.S.J., M.H.P.).
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!